456例泌尿生殖道支原体感染耐药性分析

目的分析泌尿生殖道主要感染菌及耐药性。方法泌尿生殖道支原体感染患者456例,进行支原体培养和药敏试验。结果主要感染菌是Uu、Mh和Uu+Mh,女性明显高于男性(78.08%vs 47.31%,P<0.05);最敏感药物为强力霉素、交沙霉素、美满霉素和四环素,敏感度为82%~99%。单纯Uu感染对环丙沙星(74.46%)、氧氟沙星(59.74%)、司帕沙星(48.49%)耐药性高;单纯感染Mh菌株对红霉素(95.46%)、阿奇霉素(90.91%)、克拉霉素和罗红霉素(86.36%)耐药性高;Uu+Mh感染对罗红霉素(97.22%)、红霉素(94.44%)及阿奇霉素和氧氟沙星(91.67%)耐药性高。结论应根据病原菌种类和药敏试验选择抗生素。

Drug resistance analysis of 456 cases of mycoplasma infection in urogenital tract

Objective To study the main infection genitourinary and the drug resistance of mycoplasma infection in uro- genital tract. Methods Selected 456 patients with mycoplasma infection in urogenital culture identification and drug sensitivity test. Results The main pathogenic bacteria of female infection （78.08%）, significantly higher than the 97 male cases of infection tract, and tested with mycoplasma was Uu, Mh and Uu＋Mh.196 cases （47.31%）, the difference was sta- tistically significant （P〈0.05）. The most sensitive drug were doxycycline, josamycin, minocycline and tetracycline.The sensitivity was between 82%~99%.The simple Uu infection to high antibiotic resistance was ciprofloxacin （74.46%）, ofloxacin （59.74%） and sparfloxacin （48.49%）. The simple Mh infection to high antibiotic resistance was erythromycin （95.46%）, azithromycin （90.91% ）, clarithromycin and roxithromycin （86.36%）. Uu＋Mh mixed infection to high antibiotic resistance was roxithromycin （97.22%）, erythromycin （94.44%） and azithromycin and ofloxacin （91.67%）. Conclusion We should choose antibiotics according to the infection of Mycoplasma species and drug sensitive test.