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| HPLC法测定康欣胶囊中二苯乙烯苷的含量 | |
| 引用本文： | 林武俊,陈小玉,刘可福,王红梅.HPLC法测定康欣胶囊中二苯乙烯苷的含量[J].海峡药学,2011,0(8):80-82. |
| 作者姓名： | 林武俊 陈小玉 刘可福 王红梅 |
| 作者单位： | 1. 福州屏山制药有限公司 福州350007 2. 福建中正药业有限公司 福州350004 3. 福建省汀州医院长汀366300 |
| 摘 要： | 目的采用高效液相色谱法测定康欣胶囊中二苯乙烯苷的含量。方法色谱柱为Shimpack Vp-ods（4.6mmⅹ15cm）C18柱,流动相为：乙腈∶水（15∶85）;流速：1.0mL.min-1,检测波长为320nm。结果二苯乙烯苷的进样量在0.0805μg~4.0250μg范围内与峰面积呈良好线性关系（r=0.9985）;平均回收率为96.48%,RSD为0.32%（n=6）。结论该法简便,结果可靠,可有效地用于康欣胶囊的质量控制。 |
| 关 键 词： | 二苯乙烯苷 康欣胶囊 高效液相色谱法 含量测定 |
Determination of Tetrahydroxystilbene Glucoside in Kangxin capsule by HPLC |
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| LIN Wu-jun,CHEN Xiao-yu,LIU Ke-fu,WANG Hong-mei.Determination of Tetrahydroxystilbene Glucoside in Kangxin capsule by HPLC[J].Strait Pharmaceutical Journal,2011,0(8):80-82. | |
| Authors: | LIN Wu-jun CHEN Xiao-yu LIU Ke-fu WANG Hong-mei |
| Affiliation: | LIN Wu-jun1,CHEN Xiao-yu2,LIU Ke-fu3,WANG Hong-mei1(1.Fuzhou Pingshan Medicine Limited Company,Fuzhou 350007,China,2.Fujian Zhongzheng Medicine Limited Company,Fuzhou 350004,3.Fujian Tingzhou Hospital Changting Fujian 366300,China) |
| Abstract: | OBJECTIVE The content of Tetrahydroxystilbene Glucoside in Kanxin Capsule was determined by HPLC.METHODS The chromatographic column was Shimpack Vp-ods(4.6mmⅹ15cm) C18.The mobile phase was acetonitrile-water(15∶85).The flow rate was 1.0mL·min-1 and the detection wavelength was 320nm.The external standard and peak area method were used to determine geniposide Tetrahydroxystilbene Glucoside content.RESULTS There was a good linear relationship between geniposide and peak area when the sample injection was from 0.0805~4.0250μg(r=0.9985).The average recovery of adding sample was 96.48% and RSD was 0.32%(n=6).CONCLUSION This method is simple and believable.It can be effectively used for the quality control of Kanxin Capsule. |
| Keywords: | Tetrahydroxystilbene Glucoside Kanxin Capsule HPLC Determination |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
