| 他唑西林与乳酸钠林格氏液配伍稳定性考察 |
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| 引用本文： | 刘环香,颜玉莲,刘晖,尹武华.他唑西林与乳酸钠林格氏液配伍稳定性考察[J].儿科药学杂志,2003,9(1):6-7. |
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| 作者姓名： | 刘环香 颜玉莲 刘晖 尹武华 |
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| 作者单位： | 武汉大学人民医院药学部,湖北武汉,430060 |
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| 摘 要： | 目的：考察哌拉西林钠/他唑巴坦钠与乳酸钠林格氏注射液配伍的稳定性。方法：以HPLC法测定哌拉西林钠和他唑巴坦钠的含量，并考察微粒数和pH值的变化。结果：在1.5h时哌拉西林钠含量90.13%。他唑巴坦钠含量99.8%,2.0h叶哌拉西林和他唑巴坦钠的含量下降至83.34%,98.83%。结论：注射用哌拉西林钠/他唑巴坦钠不宜与乳酸钠林格氏注射液配伍。
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| 关 键 词： | HPLC 他唑西林 乳酸钠林格氏注射液 配伍 |
| 文章编号： | 1672-108X(2003)01-0006-02 |
| 修稿时间： | 2002年7月23日 |
Studies on stability of piperacillin sodium/tazobactam sodium for injection in sodium lactate Ringer's injection |
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| LIU Huanxiang,YAN Yulian,LIU Hui,YIN Wuhua.Studies on stability of piperacillin sodium/tazobactam sodium for injection in sodium lactate Ringer''''s injection[J].Journal of Pediatric Pharmacy,2003,9(1):6-7. |
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| Authors: | LIU Huanxiang YAN Yulian LIU Hui YIN Wuhua |
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| Abstract: | Objective: To study the stability of piperacillin sodium/tazobactam sodium for injection in sodium lactate Ringer's injection. Methods: Piperacillin sodium and tazobactam sodium are determined by high performance liguid chromatography and pH value is observed. Results: The content of piperacillin is 90. 13% , tazobactam 99. 8% in 1. 5 h, piperacillin 83. 34%, and tazobactam 98. 83% in 2. 0 h. Conclusion: Piperacillin sodium and tazobactam sodium for injection can't compatible with sodium lactate Ringer's injection. |
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| Keywords: | HPLC Piperacillin sodium/tazobactam sodium Sodium lactate Ringer's injection Compatible |
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