广州市原发性肝癌的病因流行病学调查

为了调查广州市原发性肝癌（PHC）的病因因素，本研究对100例原发性肝癌作了病例对照研究。单因素分析表明，HBV感染与PHC关系最密切。此外，HCV感染、社会心理因素、肝炎家族史、单独厨房及抽油烟机的缺乏、食鱼生食物可能与PHC的发生有关。logistic多因素分析表明，HBV感染、HCV感染、负性事件、单独厨房、食鱼生食物与广州地区PHC的发生有关。值得注意的是以上因素间的协同作用，尤以HBV与其他因素间的协同作用更为明显。

An Epidemiological Study on the Etiology of Primary Hepatocellutar Carcinoma in Guangzhou,Guangdong Province

To assess the roles of suspected etiological factors in the pathogenic course of primary hepatocellular carcinoma (PHC) in Guangzhou city, a case control study including 100 cases and 100controls were matched on sex, age, occupation, education degree of was carried out. The results from single factor analyss showed that factors as HBV infection, HCV infection, psychosocial factor, lack of separate kitchen and exhausting hood, habit of eating raw fish meat were related to PHC. Logistic regression analysis showed that HBV, HCV infection, psychic trauma, personality, separate kitchen, habit of eating raw fish meat might be regarded as risk factors for PHC in Guangzhou city. It is noticeable that a significant synergic effect was observed when some factors woked jointly.