| L-鸟氨酸发酵培养基的中心复合法优化 |
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| 引用本文： | 万红贵,叶慧,陆彬,王涛,朱庆平.L-鸟氨酸发酵培养基的中心复合法优化[J].食品与发酵工业,2006,32(1):37-40. |
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| 作者姓名： | 万红贵 叶慧 陆彬 王涛 朱庆平 |
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| 作者单位： | 南京工业大学制药与生命科学学院,南京,210009 |
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| 摘 要： | 考察不同碳氮源对Corynebacterium glutamicum1006发酵产L-鸟氨酸的影响,并借助于statistica6.0数学分析软件,采用Plackett-Burman试验设计及中心复合试验设计分析法,对L-鸟氨酸产生菌1006进行了发酵培养基的优化研究。优化后的发酵培养基使1006菌株的L-鸟氨酸产率提高了44.03%。
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| 关 键 词： | L-鸟氨酸 发酵 Plackett-Burman 中心复合设计 |
| 收稿时间： | 09 19 2005 12:00AM |
| 修稿时间： | 2005年9月19日 |
Optimization of the Medium for L-ornithine Fermentation Using Central Composite Design |
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| Wan Honggui,Ye Hui,Lu Bin,Wang Tao,Zhu Qingping.Optimization of the Medium for L-ornithine Fermentation Using Central Composite Design[J].Food and Fermentation Industries,2006,32(1):37-40. |
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| Authors: | Wan Honggui Ye Hui Lu Bin Wang Tao Zhu Qingping |
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| Affiliation: | College of Pharmacy and Life Science, Nanjing University of Technology, Nanjing 210009, China |
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| Abstract: | The effects of different carbon sources and nitrogen sources on the fermentation of L-ornithine were investigated.The static culture media of Corynebacterium glutamicum 1006 producing L-ornithine was optimized using Statistic 6.0 software combined with the Plackett-Burman design and central composite design method.It is found that the L-ornithine yield with Corynebacterium glutamicum 1006 was increased by 44.03% using the optimized medium. |
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| Keywords: | Plackett-Burman |
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