阻塞性睡眠呼吸暂停综合征矫治后的上气道磁共振影响改变

目的探讨阻塞性睡眠呼吸暂停综合征（ｏｂｓｔｒｕｃｔｉｖｅ ｓｌｅｅｐ ａｐｎｅａ ｓｙｎｄｒｏｍｅ，ＯＳＡＳ）患者戴用口腔矫治器后，其上气道磁共振（ｍａｇｎｅｔｉｃ ｒｅｓｏｎａｎｃｅ ｉｍａｇｉｎｇ，ＭＲＩ）影像发生的改变。方法 选择１１例有治疗前后多导睡眠图评价、磁共振影像资料完整的ＯＳＡＳ患者，用于研究矫治器对上气道的形态学改变；另选１１名性别、年龄配比的无睡眠呼吸障碍者，作为ＭＲＩ三维形态

Magnetic resonance imaging in dental appliance treatment of obstructive sleep apnea syndrome]

OBJECTIVE: To investigate the upper airway changes after wearing dental appliance in obstructive sleep apnea syndrome(OSAS). METHODS: The research included 11 aged OSAS patients and 11 matched controls. Through dental appliance therapy the OSAS was proved by polysomnography to have ideal treatment results (AHI had decreased from 44.6 +/- 22.5 per hour to 7.53 +/- 6.44 per hour). Magnetic resonance imaging (MRI) had been performed before and after wearing dental appliance. The MRI images of upper airway after wearing dental appliance were compared with those of without wearing, and even with those of the controls. RESULTS: After wearing dental appliance the size of upper airway increased greatly, from 12.27 ml +/- 4.13 ml to 13.93 ml +/- 4.58 ml(P < 0.01), While the size of oropharynx was increased from 5.55 ml +/- 2.10 ml to 6.88 ml +/- 2.26 ml (P < 0.001). There was still remained significant difference at nasopharynx, soft palate and tongue compared with the matched controls. CONCLUSION: Dental appliance worked with the effect of enlarging upper airway. The abnormal airway morphology can not be changed completely by dental appliance treatment. MRI technique, especially the 3-D reconstruction model of upper airway, is an effective and special method in OSAS research.