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良性前列腺增生中的高度前列腺上皮内瘤初步观察
引用本文:卢慕峻,姚德鸿,蔡军,赵雁飞,林梅绥,束木娟,王炜.良性前列腺增生中的高度前列腺上皮内瘤初步观察[J].中国男科学杂志,2001,15(2):95-97.
作者姓名:卢慕峻  姚德鸿  蔡军  赵雁飞  林梅绥  束木娟  王炜
作者单位:1. 上海第二医科大学附属第九人民医院泌尿外科,
2. 上海第二医科大学病理教研室
3. 上海第二医科大学附属第九民医院病理科,
摘    要:本文观察良性前列腺增生(BPH)中的高度前列腺上皮内瘤(HPIN)现象。回顾性分析54例分析耻骨上前列腺摘除术患者的前列腺标本切片。统计其中HPIN的发生率,并结合患者术前PSA值,分别HPIN与非HPIN之间的血PSA值差别。结果发现54例患者中22例有HPIN表现,占总数的40.7%。HPIN组与非HPIN组之间的血PSA值无显著性差异。在本组BPH患者中,HPIN表现占有一定比例,因此认为HPIN现象并非前列腺癌(Pca)专用。本组中HPIN比例偏高与患者平均年龄较大有关。本研究通过血PSA测定尚无法简单区分HPIN和非HPIN。对于HPIN现象,一方面应提高警惕,密切随访;另一方面也不必盲目悲观,毕竟HPIN只是一种前列腺癌的前驱表现,而并不等于同于前列腺癌。

关 键 词:良性前列腺增生  高度前列腺上皮内瘤  前列腺特异抗原
修稿时间:2000年1月25日

Initial observation of high grade prostatic intraepithelial neoplasia in benign prostate hyperplasia
Lu Mujun,Yao Dehong,Cai Jun,et al.Initial observation of high grade prostatic intraepithelial neoplasia in benign prostate hyperplasia[J].Chinese Journal of Andrology,2001,15(2):95-97.
Authors:Lu Mujun  Yao Dehong  Cai Jun  
Affiliation:Shanghai 200011
Abstract:suprapubic prostatectomy specimens were retrospectively analysed.The results showed 22 HPIN (40.7%) in total 54 specimens.The pre operational PSA values between HPIN and non-HPIN were also compared.The PSA values had no difference between two groups (HPIN and non-HPIN).In this BPH series,HPIN is not a rare phenomenon.HPIN was not only found in prostate cancer (Pca).May be the old age caused the high percentage of HPIN.PSA can not be an exclusive index to distinguish HPIN and non-HPIN.If HPIN was found,careful followup should be done.On the other hand,HPIN was just a precursor of Pca,not Pca itself.
Keywords:benign prostate hyperplasia  high grade prostatic intraepithelial neoplasia  prostate specific antigen(PSA)
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