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85例肝硬化患者凝血指标和D-二聚体检测分析
引用本文:程玲,马芳芳,王厚照.85例肝硬化患者凝血指标和D-二聚体检测分析[J].检验医学与临床,2010,7(18):1928-1928,1931.
作者姓名:程玲  马芳芳  王厚照
作者单位:福建省厦门市解放军第174医院检验科,361003
摘    要:目的探讨肝硬化患者凝血指标-凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、血浆纤维蛋白原(FIB)、凝血酶时间(TT)和D-二聚体(D-D)检测的临床意义。方法采用ILACL-TOP全自动血凝仪对85例肝硬化患者和60例健康体检者进行PT、APTT、FIB、TT及D-D的检测。结果与健康对照组比较,肝硬化组PT、APTT、TT均延长,FIB减少,D-D增加,差异有统计学意义(P0.01)。结论凝血指标和D-二聚体的检测,对判断肝硬化患者凝血功能状况、出血危险性及治疗预后具有一定的参考价值。

关 键 词:肝硬化  凝血指标  D-二聚体

The clinical significance of coagulation index and D-D detection in patients with cirrhosis
CHENG Ling,MA Fang-fang,WANG Hou-zhao.The clinical significance of coagulation index and D-D detection in patients with cirrhosis[J].Laboratory Medicine and Clinic,2010,7(18):1928-1928,1931.
Authors:CHENG Ling  MA Fang-fang  WANG Hou-zhao
Affiliation:.Department of Clinical Laboratory of the 174th Hospital of PLA,Xiamen,361003 China
Abstract:Objective To explore the clinical significance of detecting prohtrombin time(PT),actived partial thromboplatin time(APTT),fibrinogen(FIB),thrombin time(TT)and D-dimer(D-D)in the patients with cirrhosis.Methods PT,APTT,FIB,TT and D-D were detected in 85 patients with cirrhosis and 60 healthy people by IL ACL-TOP Auto Blood Coagulation Analyzer.Results The PT,APTT,TT prolonged,FIB decreased and D-D increased in the patients compared with the control,and showed significant difference(P0.01).Conclusion The coagulation index and D-D detection has a reference value in estimating the coagulation function,the hemorrhagic tendency,the treatment and prognosis in the patients with cirrhosis.
Keywords:cirrhosis  coagulation index  D dimer
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