| 晚期非小细胞肺癌维持治疗的研究进展 |
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| 引用本文： | 沈玉萍,张西,许青.晚期非小细胞肺癌维持治疗的研究进展[J].上海医药,2013(23):15-18. |
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| 作者姓名： | 沈玉萍 张西 许青 |
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| 作者单位： | 同济大学附属第十人民医院肿瘤科,上海200072 |
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| 摘 要： | 维持治疗分为继续维持治疗和换药维持治疗。研究证实，培关曲塞是一种既可用于换药维持治疗、也可用于继续维持治疗的晚期非小细胞肺癌化疗药物。另外，酪氨酸激酶抑制剂亦是一类非常有效的维持治疗选择，其中吉非替尼和厄洛替尼已被有关指南推荐用作维持治疗药物，但目前只能用于换药维持治疗。
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| 关 键 词： | 晚期非小细胞肺癌 维持治疗靶 向治疗 |
Maintenance therapy of advanced non-small-cell lung cancer |
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| SHEN Yuping,ZHANG Xi,XU Qing.Maintenance therapy of advanced non-small-cell lung cancer[J].Shanghai Medical & Pharmaceutical Journal,2013(23):15-18. |
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| Authors: | SHEN Yuping ZHANG Xi XU Qing |
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| Affiliation: | (Department of Oncology, the 10th People＇s Hospital of Shanghai, Tongji University, Shanghai 200072, China) |
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| Abstract: | Maintenance therapy can be usually divided into continuation-maintenance and switch-maintenance. It is confirmed that the pemetrexed could be used as both continuation-maintenance drugs and switch-maintenance drugs in the treatment of advanced non-small-cell lung cancer. Tyrosine kinase inhibitors is another effective maintenance drugs, in which gefitinib or erlotinib has been recommended as a maintenance therapy drug in some guideline, however either one can be only used for switch-maintenance now. |
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| Keywords: | advanced non-small-cell lung cancer maintenance therapy targeted therapy |
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