160例SARS患者心脏变化的观察

目的　探讨 SARS感染后是否导致心肌受损。方法　入院第二日 ,监测血清酶 AST、AL T、L DH、CK、CKMB及 HBDH,并连续观察 ,拍胸片 ,记录症状 ,对部分患者于出院后 2周进行复查。结果　 16 0例患者中呼吸困难 6 3例 ,心悸 6 1例 ,肌肉痛 37例 ;112例有不同程度的心肌酶升高 ,谷丙转氨酶 (AL T) /谷草转氨酶 (AST) <1,普通型及重型分别为 3例 (3/ 10 8)和 31例 (31/ 5 3) ;X线检查心胸比例 >0 .6普通型及重型分别为 3例 (3/ 10 8)和 39例 (39/ 5 2 )。出院复查 5 1例患者 9例心肌酶异常 ,窦性心动过速 3例 ,其余正常。结论　 SARS病毒感染后可能会导致心肌一过性损害。

Clinical Analysis of the Changes of Heart Status of 160 SARS Patients

Objective To investigate the heart changes of severe acute respiratory syndrome (SARS) patients.Methods The patients were divided into two groups:ordinary group and severe group. Serum enzymes (AST, ALT, LDH, CK, CKMB) we reexamined on the second day after admission. Symptoms were observed and X-rays were checked. Some discharged patients were checked in two weeks after leaving hospital. Results Of the 160 patients, short breath was present in 63 (38.9%), palpitation in 61 (38.1) and myalgia in 37 (23.1%). Serum ALT/AST was less than 1 for the ordinary group. And for the severe group, the respective figures were 3 (2.8%, 3/108) and 31(59.6%, 31/52).. In chest radiograph examination, the proportion of heart and chest diameter was above 0.6 for the ordinary group, and for the severe group the respective figures were 3 (2.8% 3/108) and 39 (75.0%, 39/52). Of 51 discharged patients, serum enzymes were abnormal in 9. All patients were normal with ECG with an exception of 3 patients with tachycardia.Conclusion SARS may be associated with harm on heart.