| 冷适应对钴-60照射大鼠应激反应的影响 |
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| 引用本文： | 谢怀江,于宁,金焕荣.冷适应对钴-60照射大鼠应激反应的影响[J].中国辐射卫生,2004,13(3):166-167. |
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| 作者姓名： | 谢怀江 于宁 金焕荣 |
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| 作者单位： | 1. 沈阳军区疾病预防控制中心, 辽宁沈阳 110034;2. 沈阳医学院 |
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| 摘 要： | 目的 研究冷适应是否会引起辐射敏感性的变化。方法 对冷适应后大鼠进行钴-60照射,测定其血中肾上腺素(ADR)、去甲肾上腺素(NAD)及一氧化氮(NO)含量。结果 冷适应后可以明显降低由于辐射而引起的心率加快,明显减轻由于单纯照射造成的NO降低,还可以减轻由于辐射而引起的ADR的升高。结论 冷适应可能降低单纯照射引起的应激反应。
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| 关 键 词： | 冷适应 电离辐射 应激反应 |
| 文章编号： | 1004-714X(2004)03-0166-02 |
| 收稿时间： | 2004-03-17 |
| 修稿时间： | 2004年3月17日 |
Stress Response Exposed to Irradiation after Cold - adaptation in Rats |
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| XIE Huai-jiang. YU Ning,JIN Huan-rong.Stress Response Exposed to Irradiation after Cold - adaptation in Rats[J].Chinese Journal of Radiological Health,2004,13(3):166-167. |
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| Authors: | XIE Huai-jiang YU Ning JIN Huan-rong |
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| Affiliation: | Center of Disease Control, Shenyang District, PLA, 110034, China |
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| Abstract: | Objective To observe the effects of radiosensitivity in cold-adaptation.Methods Male Wastar rats were exposed to 4 Gy 60Co γ-ray irradiation after cold-adaptation for 4 weeks at (4±2)℃.The change of nitric oxide (NO), adrenalin (ADR) and noradrenalin (NAD) in blood were observed.Results The results showed that treatment with cold-adaptation could increase the level of NO by irradiation, and attenuat the production of the ADR level in blood.Conclusion It is suggested that the cold-adaptation should attenuate the effect of stress response exposed to irradiation. |
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| Keywords: | Cold-adaptation Irradiation Iipid Peroxidation(LPO) Stress Response |
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