新装修房屋室内空气污染对人体血液流变学影响的调查

目的探讨新装修房屋室内空气污染与人体血液流变学各指标的影响关系及其影响机制。方法对新装修房屋室内空气进行甲醛、苯、甲苯、二甲苯(苯系物)的测定,对住户进行血液流变学、血常规、血糖检测,同时进行既往病史和现病史问卷调查。筛选无糖尿病、肾病、肝病、血液病病史且血液流变学指标增高的人群作为研究对象,统计分析其血液流变学各指标增高与所居住的房屋空气中甲醛、苯系物浓度的关系。结果研究对象全血黏度的增高与甲醛、二甲苯有关,血浆黏度与污染物无相关性。甲醛对全血黏度超标的发生的贡献大于二甲苯。甲醛浓度与全血黏度增高呈正相关关系。结论甲醛超标是人体全血黏度增高的主要原因,其机制可能与其对红细胞膜脂质的过氧化损伤有关。

Study on influence of air pollution of new decoration house on human hemorheology

Objective To research the influence of air pollution of new decoration house on the indicators of human hemorheology and to analyse its influencing mechanism.Methods Formaldehyde and benzene,toluene,xylene(benzene series) in air of new decoration house were detected.Hemorheology,blood routine and plasma glucose in the inhabitants were detected.The past and present medical history in the inhabitants were investigated by questionnaire survey.The crowds with normal detection results of blood routine,plasma glucose and without diabetes mellitus,kidney disease,liver disease and hematological disease were screened out for the study subjects.The relation between the concentration of formaldehyde and benzene series in the air of new decoration houses with the increased indicators of hemarheology was statistically analyzed.Results The rise of whole blood viscosity in the study subjects was related to formaldehyde and xylene.The plasma viscosity was not related to formaldehyde and benzene series.Formaldehyde′ s contribution to the exceeding standard of whole blood viscosity was more than xylene′ s.There was a positive correlation between the whole blood viscosity and concentration of formaldehyde.Conclusion The exceeding standard of formaldehyde is the main reason for whole blood viscosity rising.The mechanism of whole blood viscosity rising could be related to the peroxidation harm of erythrocyte membrane lipid.