| 肺癌患者SCC、CYFRA211、NSE和CEA检测的临床意义 |
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| 引用本文： | 魏善和,朱召明,闫丽妲,邓芳,吴丽.肺癌患者SCC、CYFRA211、NSE和CEA检测的临床意义[J].牡丹江医学院学报,2010,31(1):18-21. |
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| 作者姓名： | 魏善和 朱召明 闫丽妲 邓芳 吴丽 |
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| 作者单位： | 枣庄市陶庄镇枣庄矿业集团中心医院,山东,枣庄,277011 |
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| 摘 要： | 目的：探讨血清肿瘤标记物鳞状细胞癌相关抗原（SCC-Ag）、细胞角蛋白19血清片段211（CYFRA211）、神经元特异性烯醇化酶（NSE）,癌胚抗原（CEA）在肺癌临床诊断中的价值。方法：采用酶联免疫法检测109例肺癌病人及48例肺良性病变病人血清SCC-Ag,CYFRA2ll和NSE的水平,化学发光法测定CEA的水平。结果：肺癌组血清四项肿瘤标记物的含量均高于肺良性病变组（P〈0.01）,SCC水平在肺鳞癌中明显升高;CYFRA211水平以非小细胞肺癌（NSCLC）升高明显;NSE以小细胞肺癌（SCLC）升高为明显;CEA以肺腺癌增高为主;SCC,CYFRA211,NSE,CEA及四项联合检测诊断肺癌的灵敏度分别49.5%,45.9%,56.9%,21.1%。结论：SCC对鳞癌、CYFRA211对非小细胞肺癌（NSCLC）,NSE对小细胞肺癌（SCLC）,CEA对腺癌具有较大的辅助诊断价值,四项联合检测提高肺癌诊断的灵敏度、准确率。
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| 关 键 词： | 鳞状细胞癌相关抗原 细胞角蛋白19血清片段211 神经元特异性烯醇化酶 癌胚抗原 肺癌 |
CLINICAL DIAGNOSTIC SIGNIFICANCE OF SCC,CYFRA211,NSE AND CEA FOR LUNG CANCER |
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| Wei Shanhe etal.CLINICAL DIAGNOSTIC SIGNIFICANCE OF SCC,CYFRA211,NSE AND CEA FOR LUNG CANCER[J].Journal of Mudanjiang Medical College,2010,31(1):18-21. |
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| Authors: | Wei Shanhe etal |
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| Affiliation: | Central Hospital of Zaozhuang Coal Mining Group Co.LTD zaozhuang Shandong 277011 |
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| Abstract: | Objective:To appraise the values of tumor markers of SCC,CYFRA211,NSE and CEA in the diagnosis of lung cancer.Methods:The levels of SCC,CYFRA211,NSE and CEA were measured by electrochemiluminescence in serum of 109 patients with lungc ancer and 48 patients with benign lung diseases.Results:The levels of SCC,CYFRA211,NSE and CEA in cancer patients were significantly higher than that of the patients with benign ones(P<0.01)In comparison with patients with benign rumor,those lung cancer patients showed the fol... |
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| Keywords: | SCC CYFRA211 NSE CEA lungc ancer |
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