黄芪甲苷氯化钠注射液治疗冠心病心绞痛220例安全性及有效性评价

目的]客观评价黄芪甲苷氯化钠注射液治疗冠心病心绞痛的有效性和安全性.方法]试验组给予黄芪甲苷氯化钠注射液,对照组给予丹参注射液,疗程14 d,分别对心电图疗效、硝酸甘油停减率、中医证候疗效的变化进行观察.结果]黄芪甲苷氯化钠注射液能够改善心电图表现,心电图疗效试验组优于对照组,具有显著性差异(P＜0.05);具有改善中医证候疗效的作用(P＜0.05),特别是气虚血瘀证患者疗效显著(P＜0.05);硝酸甘油用量停减率,两组比较差异无统计学意义(P＞0.05);试验过程中,试验组未发生不良事件和不良反应.结论]黄芪甲苷氯化钠注射液治疗冠心病心绞痛安全有效.

Evaluation of safety and efficacy of astragali glycoside sodium chloride injection on treating heartstroke of coronary heart disease

Objective] To evaluate the safety and efficacy of astragali glycoside sodium chloride injection on treatingheartstroke ofcoronaryheart disease.Methods] The patients oftreatment group was administrated to astragali glycoside sodium chloride injection and that of control group was administrated to Salvia miltiorrhiza injection.The course of treatment was fourteen days.To observe the electrocardiogram effect,nitroglycerol stopping and decreasing rate,curative effect of TCM syndrome.Results] The astragali glycoside sodium chloride injection may improve the electrocardiogram and curative effect of TCMsyndrome.The patients of treatment group had obviously an advantage than that of control group on the improvement of electrocardiogram (P<0.05).The patients of treatment group had obviously an advantage than that of control group on the improvement of TCMsyndrome (P<0.05).The patients of treatment group hadn't obviously an advantage than that of control group on the improvement of nitroglycerol stopping and decreasing rate (P>0.05).The patients of treatment group hadn't badness incident and adverse effect.Conclusion] The astragali glycoside sodium chloride injection was safe and effective to treating heartstroke of coronary heart disease.