绝经前女性并发急性冠状动脉综合征的临床特征分析

目的探讨绝经前女性并发急性冠脉综合征（ACS）的特点。方法回顾性分析2007年10月～2011年10月我院收治的128例绝经前女性急性胸痛患者（ACS组）及100例早发男性患者（对照组）临床资料,记录并分析其造影特点、临床特点和危险因素。结果 ACS组合并原发性高血压、高脂血症、糖尿病比例较对照组明显升高（P〈0.05）;两组在单支病变及冠状动脉正常比例方面比较,差异均有高度统计学意义（P〈0.01）;低密度脂蛋白胆固醇（LDL-C）可作为影响绝经前女性并发ACS的主要因素。结论高血压、高脂血症是绝经前女性最重要的冠心病危险因素,该病的发生、发展可能与内源性雌激素的变化有关。

Clinical characteristics analysis of premenopause women with acute coronary syndromes

Objective To investigate the characteristics of premenopause women with acute coronary syndromes（ACS）.Methods The clinical data of 128 cases of premenopause women with acute coronary syndromes（ACS group） and 100 cases of early onset men（control group） from October 2007 to October 2011 in our hospital were retrospectively analyzed.The coronary angiographic features,clinic features and the risk factors were recorded and studied.Results The rates of high blood pressure,hyperlipidemia,diabetes in ACS group were higher than that in the control group（P 0.05）;the differences of the rates of single lesions and coronary artery normal in two groups were statistically significant（P 0.01）;LDL-L could be the main factors of ACS to influence the premenopausal women.Conclusion High blood pressure,hyperlipidemia is the most important risk factors of coronary heart disease for premenopausal women,the occurrence and development of the disease may be relevanted with the change of endogenous estrogen.