| 脂质组学及其在营养与健康研究中的应用研究进展 |
| |
| 引用本文： | 陈宇欢,李静,范亚苇,邓泽元.脂质组学及其在营养与健康研究中的应用研究进展[J].食品科学,2014,35(15):272-276. |
| |
| 作者姓名： | 陈宇欢 李静 范亚苇 邓泽元 |
| |
| 作者单位： | 南昌大学 食品科学与技术国家重点实验室，江西 南昌 330047 |
| |
| 基金项目： | 国家自然科学基金地区科学基金项目(31060214);江西省自然科学基金项目(2009GZY0148) |
| |
| 摘 要： | 脂质是生物体重要的大分子物质之一，结构和种类复杂，具有重要的生理功能。脂质代谢的异常可能引发诸如动脉粥样硬化等许多代谢疾病。脂质代谢组学是代谢组学的一个分支，是综合研究脂质代谢的一个重要手段。随着质谱与色谱联用技术的发展，脂质组学也得到快速发展。利用脂质组学研究脂质分子在代谢疾病中的作用受到越来越广泛的关注。本文主要介绍了脂质组学的研究方法，及其在人体脂质代谢疾病中的应用和研究进展。
|
| 关 键 词： | 脂质组学 研究进展 代谢疾病 营养 |
Lipidomics and Its Application in Nutrition and Health Research |
| |
| CHEN Yu-huan,LI Jing,FAN Ya-wei,DENG Ze-yuan.Lipidomics and Its Application in Nutrition and Health Research[J].Food Science,2014,35(15):272-276. |
| |
| Authors: | CHEN Yu-huan LI Jing FAN Ya-wei DENG Ze-yuan |
| |
| Affiliation: | State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China |
| |
| Abstract: | Lipids, compounds with complex structures and classes, are one important class of biomacromolicules in organisms.
Abnormal lipid metabolisms may lead to many metabolic diseases, such as atherosclerosis. Lipidomics, a sub-branch of
metabonomics, is an important approach aiming at comprehensive analysis of lipid metabolisms. Recent advancements in mass
spectrometry combining with chromatography have led to the rapid development of lipidomics. Investigating the role of lipid
molecules in metabolic diseases has attracted increasing attention. In this review, we focus on the analytical approaches in used in
lipidomics research, and recent advances in their applications in the field of nutrition and health. |
| |
| Keywords: | lipidomics progress metabolic disease nutrition |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《食品科学》浏览原始摘要信息 |
|
点击此处可从《食品科学》下载全文 |
