红细胞分布宽度与慢性心力衰竭预后的关系

目的分析红细胞分布宽度（redbloodcellvolumedistributionwidth．RDW）与慢性心力衰竭（chronicheartfailure，CHF）预后的关系，并探讨其在CHF中作为一种新的诊断标志物的可能性。方法收集2009年5月至2010年12月我院CHF患者共200例，根据纽约心功能分级分为心功能Ⅱ级组（n=66）、心功能Ⅲ级组（n=58）、心功能Ⅳ级组（n=76）；另选182例同期住院健康体检者作为对照组．比较各组之间的RDW；将CHF患者分为RDW增高组（n=102）和RDW正常组（n=98），比较两组间的病死率。结果各组间一般资料比较差异均无统计学意义（P均〉0．05）。从对照组到心功能Ⅳ级组，RDW逐渐增加，各组间两两比较差异均具有统计学意义（P均〈0．01）；RDW增高组CHF患者病死率较RDW正常组明显升高，且差异有统计学意义（P〈0．05）。结论CHF患者RDW明显升高，且其人院时RDW水平与慢性不良事件的发生和预后存在明显相关性。

The relationship between red blood cell volume distribution width and the prognosis of chronic heart failure

Objective To study the relationship between red blood cell volume distribution width （RDW） and the prognosis of chronic heart failure （CHF）, and to explore its possible as a potentially novel lab- oratory markers in CHF patients. Methods 200 patients with CHF in our hospital from May 2009 to December 2010 were collected and divided into three groups according to New York Heart Association： class Ⅱ （n= 66）, class Ⅲ （n= 58）, class 1V （n= 76） ; 182 cases healthy people as the control group. The levels of RDW were compared in all groups ; 200 patients with CHF were divided into two groups, normal RDW group （n= 98 ） and high RDW group （n= 102）, The mortality were compared in two groups. Results There were no statistical significance among all the groups in the differences of clinical data （Pall〉 0.05）. The levels of RDW increased gradually from control group to class 1V group, and there were statistical significance between each two groups （Pall〈 0.01 ）. The mortality in higher RDW group was higher than in normal RDW group and the difference bad statistical significance（P〈 0.05 ）. Conclusion RDW in CHF patients is significantly higher than in the control group, and the level of RDW is obviously related with the prognosis of CHF.