| Bcl-2与子宫内膜异位症发病关系的研究 |
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| 引用本文： | 毛熙光,林海蕤,高谨,秦明丽,邱盛洪.Bcl-2与子宫内膜异位症发病关系的研究[J].泸州医学院学报,2004,27(3):196-198. |
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| 作者姓名： | 毛熙光 林海蕤 高谨 秦明丽 邱盛洪 |
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| 作者单位： | 泸州医学院附属医院妇产科,四川泸州,646000 |
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| 摘 要： | 目的 :研究Bcl- 2基因蛋白与子宫内膜异位症的发病关系。方法 :用免疫组化ABC法检测了 4 0例正常子宫内膜和 4 6例子宫内膜异位症患者异位内膜组织中Bcl- 2蛋白的表达情况。结果 :Bcl- 2基因蛋白在子宫内膜异位症患者的异位内膜组织中的表达评分 (172 .4± 87.6 )明显高于正常子宫内膜中的表达评分 (10 6 .2±118.1) ,有显著性差异 (P <0 .0 1)。结论 :Bcl- 2基因与子宫内膜异位症的发生有一定关系。
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| 关 键 词： | 子宫内膜异位症 细胞凋亡 基因 Bcl-2 |
| 文章编号： | 1000-2669(2004)3-0196-03 |
| 修稿时间： | 2003年12月4日 |
RELATION BETWEEN Bcl-2 GENE AND THE PATHOGENESIS OF ENDOMETRIOSIS |
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| Mao Xiguang,et al.RELATION BETWEEN Bcl-2 GENE AND THE PATHOGENESIS OF ENDOMETRIOSIS[J].Journal of Luzhou Medical College,2004,27(3):196-198. |
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| Authors: | Mao Xiguang |
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| Affiliation: | Mao Xiguang,et al Department of Obstetrics and Genecology,Luzhou Medical College Hospital |
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| Abstract: | Objective: To research whether the endometriosis is associated with Bcl-2 gene. Methods: Immunohistochemistry methods(ABC methods) were used to detect the expression of Bcl-2 gene in 40 specimens of normal endometrium tissue and 46 specimens of endometriosis tissue. Results: In the endometriosis group, the positive rate of Bcl-2 gene was significantly higher than that of the normal endometrium group (P<0.01). Conclusion: The study suggested that Bcl-2 gene is related with endometriosis. |
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| Keywords: | Endometriosis Bcl-2 Gene Apoptosis |
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