| 大孔吸附树脂分离纯化厚朴酚的方法研究 |
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| 引用本文： | 赵春颖,毛晓霞,张梓倩.大孔吸附树脂分离纯化厚朴酚的方法研究[J].承德医学院学报,2009,26(4):358-360. |
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| 作者姓名： | 赵春颖 毛晓霞 张梓倩 |
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| 作者单位： | 1. 承德医学院中药研究所,河北承德,067000
2. 首都医科大学 |
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| 摘 要： | 目的:研究大孔吸附树脂法分离纯化厚朴中厚朴酚的工艺,为以高纯度厚朴酚为原料开发新药奠定基础.方法:采用D-101型(非极性)、DA-201型(极性)、DM-301型(中极性)三种大孔吸附树脂对厚朴中厚朴酚进行吸附纯化,以厚朴酚纯度和吸附率为考察指标筛选最佳树脂.结果:经D-101型、DA-201型、DM-301型大孔吸附树脂分离纯化后,厚朴酚含量由7.56%分别提高到10.69%、12.72%、15.26%.结论:三种纯化方法中,以DM-301型树脂效果最佳.
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| 关 键 词： | 大孔吸附树脂 厚朴 厚朴酚 分离纯化 |
SEPARATION AND PURIFICATION OF MAGNOLOL FROM MAGNOLIA OFFICINALIS BY MACRORETICULAR RESIN |
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| ZHAO Chun-ying,MAO Xiao-xia,ZHANG Zi-qian.SEPARATION AND PURIFICATION OF MAGNOLOL FROM MAGNOLIA OFFICINALIS BY MACRORETICULAR RESIN[J].Journal of Chengde Medical College,2009,26(4):358-360. |
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| Authors: | ZHAO Chun-ying MAO Xiao-xia ZHANG Zi-qian |
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| Affiliation: | ZHAO Chun-ying,MAO Xiao-xia,ZHANG Zi-qian (Institute of Chinese Materia Medica,Chengde Medical College,Hebei Chengde 067000,China) |
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| Abstract: | Objective:To establish a technical process for separation and purification of Magnolol from Magnolia officinalis Rehd. Et Wils, and provide bases for developing new drugs.Methods:3 kinds of macroporous resin, D101, DA-201 and DM-301 were used to separate and purify Magnolol form Magnolia officinalis. The purity of Magnolol and adsorption rate was taken to choose the best resin.Results:The Magnolol content raised form 7.56% to10.69%,12.72% and 15.26% after separation and purification by 3 kinds of macroporou... |
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| Keywords: | Macroporous resin Magnolia officinali Magnolo Separation and purification |
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