| Th1、Th2、Th17型细胞因子与糖尿病肾病相关性的研究 |
| |
| 引用本文： | 赵秀玲,曹奇志.Th1、Th2、Th17型细胞因子与糖尿病肾病相关性的研究[J].医学分子生物学杂志,2021,18(1). |
| |
| 作者姓名： | 赵秀玲 曹奇志 |
| |
| 作者单位： | 菏泽市中医医院肾病科 山东省菏泽市, 274000;山东省滨州医学院(烟台校区) 免疫学教研室 山东省烟台市,264000 |
| |
| 摘 要： | 糖尿病肾病(diabetic Nephropathy,DN)是导致终末期肾脏病(end-stage renal disease,ESRD)的最主要病因,因此,早期诊断和治疗是糖尿病肾病的诊治要点。但目前糖尿病肾病的确切发病机制尚未完全明确,糖尿病肾病的发生发展与血流动力学改变和代谢的紊乱、氧化应激和炎症等多种因素有关,而细胞因子在2型糖尿病及其相关肾脏并发症的病因、发病机制中也起着重要的作用,各种细胞因子的识别将为糖尿病肾病的诊治提供新的潜在治疗靶点。文章就Th1、Th2、Th17型细胞因子与DN相关性的研究作了综述。
|
| 关 键 词： | 2型糖尿病 糖尿病肾病 Th1 Th2 Th17 |
Correlation between Th1,Th2 and Th17 Cytokines and Diabetic Nephropathy |
| |
| ZHAO Xiuling,CAO Qizhi.Correlation between Th1,Th2 and Th17 Cytokines and Diabetic Nephropathy[J].Journal of Medical Molecular Biology,2021,18(1). |
| |
| Authors: | ZHAO Xiuling CAO Qizhi |
| |
| Affiliation: | (Department of Nephropathy,Heze Hospital of Traditional Chinese Medicine,Heze,Shandong,274000,China;Department of Immunology Teaching and Research,Shandong Binzhou Medical College(Yantai Campus),Yantai,Shandong,264000,China) |
| |
| Abstract: | Diabetic Nephropathy(DN)is the main cause of end-stage renal disease(ESRD).Early diagnosis and treatment are essential for effective control of DN.However,the exact pathogenesis of DN is not yet fully understood.The occunence and development of DN is related to changes in hemodynamics and metabolic disorders,oxidative stress,inflammation and other factors.Cytokines play important roles in the etiology and pathogenesis of type 2 diabetes and DN.The identification of various cytokines will provide new potential therapeutic targets for the diagnosis and treatment of DN.This article reviews the research on the correlation between Th1-,Th2-,Th17-type cytokines and DN. |
| |
| Keywords: | type 2 diabetes diabetic nephropathy Th1 Th2 Th17 |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
