| 染发剂对豚鼠皮肤表皮和真皮超微结构的影响 |
| |
| 引用本文： | 陈丽,程基焱,郑福蓉,陈志群.染发剂对豚鼠皮肤表皮和真皮超微结构的影响[J].泸州医学院学报,2008,31(4). |
| |
| 作者姓名： | 陈丽 程基焱 郑福蓉 陈志群 |
| |
| 作者单位： | 1. 泸州医学院,公共卫生系,四川泸州646000
2. 泸州医学院,电子显微镜实验室,四川泸州646000 |
| |
| 摘 要： | 目的:探讨染发剂对豚鼠皮肤的毒性作用.方法:用市售染发剂涂抹豚鼠皮肤制作染发剂的皮肤慢性损伤动物模型,统计豚鼠的体重变化,以及用电子显微镜观察皮肤表皮和真皮的超微结构改变.结果:在8000～20000倍电子显微镜下观察,皮肤角质形成细胞及真皮成纤维细胞的细胞核、细胞器都出现不可逆转损伤.结论:50%、100%浓度的染发剂可导致豚鼠皮肤角质形成细胞和成纤维细胞发生不可逆病理改变,以及豚鼠的生长抑制等全身性影响.
|
| 关 键 词： | 染发剂 豚鼠 皮肤 |
AFFECT OF HAIR DYE ON SKIN EPIDERMIS AND CORIUM ULTRASTRUCTURE OF GUINEA PIG |
| |
| Chen Li,et al.AFFECT OF HAIR DYE ON SKIN EPIDERMIS AND CORIUM ULTRASTRUCTURE OF GUINEA PIG[J].Journal of Luzhou Medical College,2008,31(4). |
| |
| Authors: | Chen Li |
| |
| Affiliation: | Chen Li,et al Department of Public Health,Luzhou Medical College |
| |
| Abstract: | Objective: To explore the toxic effect of hair colour cosmetics on skin of guinea pig.Methods:Animal model of skin chronic damage was done through daubing the skin of guinea pig with hair colour cosmetics available on the market.Body weight change of the guinea pig and ultrastructure change of the skin epidermis and dermal in electronmicroscope.Results:The cell nucleus and cell organelle of skin Malpighian cell and dermis fibroblast showed irreversible damage under electronmicroscope.Conclusions:The hair co... |
| |
| Keywords: | Hair colour cosmetics Guinea pig Skin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
