盐酸纳洛酮注射液治疗急性脑梗死的疗效观察

目的 观察纳洛酮治疗急性脑梗死的临床治疗效果。方法 将确诊的112例急性脑梗死患，随机分为低分子右旋糖酐加复方丹参注射液对照组54例，低分子右旋糖酐500ml加复方丹参注射液16ml iv,qd,14d 一疗程。纳洛酮治疗组58例在对照组治疗基础上，用纳洛酮2.0加入生理氯化钠溶液500ml中iv,bid疗程同对照组。结果 治疗组58例，基本治愈18例，显进步23例，进步13例，无效或恶4例，总有效率为93．1％。对照组54例，基本治愈10例，显进步18例，进步15例，无效或恶化11例，总有效率为79．6％。两组比较有显性差异（P＜0．05），并未发现不良反应。结论 纳洛酮治疗急性脑梗死效果显，疗效确切，无副作用。

Effects of Naloxone Hydrochloride Injection in the treatment of patients with braindeadlock

Aim To study the therapeutic effects of Naloxone Hydrochloride Injection on braindeadlock.Methods Braindeadlock patients were treated with Naloxone Hydrochloride Injection.In control group,(N=54) the patients were treated by Injection Deneran 40 Glucose Injection 500ml mixed with Fufang dansen Injection 16ml qd,14d for a course.In therapeutic group,(N=58) the patients were treated as in control group,simultaneously were injected with Naloxone 2.0g mixed with Compound Sodium Chloride injection.Results In therapeatic group,very effective results were obtained in 18,striking improvement in 23,improvement in 13,ineffectiveness in 4,with a total efficacy rate of 93.1%,In control group,very effective results were obstained in 10,striking improvement in 18,improvement in 15,ineffectiveness in 11,with a total efficacy rate of 79.6%.There are large difference between the two groups,and side effects were not found.Conclusion Naloxone Hydrochloride Injection has striking effect in braindeadlock,and side effect was not found.