| 瑞波西汀与氟西汀治疗老年抑郁症的对照研究 |
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| 引用本文： | 刘美兰,张仲荣,张增,苏中华.瑞波西汀与氟西汀治疗老年抑郁症的对照研究[J].中国药师,2008,11(7):774-776. |
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| 作者姓名： | 刘美兰 张仲荣 张增 苏中华 |
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| 作者单位： | 济宁市精神病防治院,山东济宁,272051 |
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| 摘 要： | 目的：比较瑞波西汀与氟西汀治疗老年抑郁症的疗效和安全性。方法：用瑞波西汀与氟西汀对144例老年抑郁症患者进行为期6周的随机对照试验，用汉密顿抑郁量表（HAMD）评定疗效，用不良反应量表（TESS）评定不良反应。结果：瑞波西汀与氟西汀治疗老年抑郁症的疗效相当（P〉0.05），其显效率分别为72．3％和75％；瑞波西汀致口干、便秘、皮肤异样感等不良反应较氟西汀多，而恶心、呕吐、腹泻、嗜睡等不良反应较氟西汀少。结论：瑞波西汀治疗老年抑郁症具有良好的疗效和安全性。
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| 关 键 词： | 瑞波西汀 氟西汀 老年抑郁症 瑞波西汀 氟西汀 治疗 老年 抑郁症患者 对照研究 Depression Senile Treatment Fluoxetine Reboxetine Study 嗜睡 腹泻 呕吐 皮肤 便秘 显效率 结果 TESS |
Comparison Study of Reboxetine and Fluoxetine on Treatment of Senile Depression |
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| Liu Meilan,Zhang Zhongrong,Zhang Zeng,Su Zhonghua.Comparison Study of Reboxetine and Fluoxetine on Treatment of Senile Depression[J].China Pharmacist,2008,11(7):774-776. |
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| Authors: | Liu Meilan Zhang Zhongrong Zhang Zeng Su Zhonghua |
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| Affiliation: | Liu Meilan Zhang Zhongrong Zhang Zeng Su Zhonghua (Jining Mental Hospital,Sh,ong jining 272051,China) |
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| Abstract: | Objective:To compare the efficacy and safety of reboxetine and fluoxetine in the treatment of senile depression.Meth- od:One hundred and fourty-four patients were randomly assigned to receive reboxetine (n=72)and fluoxetine(n=72) for 6 weeks. Their efficacy were evaluated by Hamilton Depressine Scale (HAMD) and their adverse reactions were evaluated by the Treatment E- mergent Symptom Scale(TESS).Result:The efficacy of reboxetine and fluoxetine were nearly equal.The effective rates of reboxetine and fluoxet... |
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| Keywords: | Reboxetine Fluoxetine Elderly major depresson |
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