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口腔速溶膜剂的研究进展
引用本文:王倩,苏峰,刘为中,何广卫. 口腔速溶膜剂的研究进展[J]. 安徽医药, 2017, 21(3): 399-403. DOI: 10.3969/j.issn.1009-6469.2017.03.003
作者姓名:王倩  苏峰  刘为中  何广卫
作者单位:安徽中医药大学,安徽 合肥,230012;合肥医工医药有限公司,安徽 合肥,230088
基金项目:十二五国家"重大新药创制"科技重大专项项目
摘    要:口腔速溶膜剂作为一种新型的口腔黏膜吸收固体速释制剂,具有释药迅速、给药方便、病人顺应性好等优势,尤其适用于吞咽不便的儿童.目前越来越多的药物被开发成此剂型并推向市场.该研究介绍了口腔速溶膜的处方组成、制备工艺、质量评价及与其它新剂型结合应用的研究进展,以期对此类制剂的研发提供参考.

关 键 词:膜剂  口腔  药物调剂  药物评价
收稿时间:2016-10-18
修稿时间:2016-12-27

Research progress of oral fast dissolving films
WANG Qian,SU Feng,LIU Weizhong and HE Guangwei. Research progress of oral fast dissolving films[J]. Anhui Medical and Pharmaceutical Journal, 2017, 21(3): 399-403. DOI: 10.3969/j.issn.1009-6469.2017.03.003
Authors:WANG Qian  SU Feng  LIU Weizhong  HE Guangwei
Affiliation:Auhui University of Traditional Chinese Medicine,Hefei,Anhui 230012,China,Hefei Industrial Pharmaceutical Institute Co.,Ltd.,Hefei,Anhui 230088,China,Hefei Industrial Pharmaceutical Institute Co.,Ltd.,Hefei,Anhui 230088,China and Hefei Industrial Pharmaceutical Institute Co.,Ltd.,Hefei,Anhui 230088,China
Abstract:Oral fast dissolving film as a new approach to oral drug delivery system has unique advantages of rapid dissolution,convenient administration and good patient compliance.The film is especially suitable for the children who are inconvenient to swallow.Nowadays,more and more medicines have been developed into such formulations and are widely pushed into the market.By reviewing the relevant literature and report of domestic and international research on oral fast dissolving films in recent years,this article mainly summarizes the formulation,preparation,quality evaluation,and combination of new dosage forms and oral fast dissolving film,to provide reference to the research and development of such preparations.
Keywords:Membranae  Mouth  Drug compounding  Drug evaluation
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