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关联氧化还原电位的丁二酸发酵过程动力学模型
引用本文:钱飞,张湜,姜岷.关联氧化还原电位的丁二酸发酵过程动力学模型[J].化工自动化及仪表,2010,37(10):10-13.
作者姓名:钱飞  张湜  姜岷
作者单位:[1]南京工业大学自动化与电气工程学院,南京210009 [2]南京工业大学制药与生命科学学院,南京210009
基金项目:国家自然科学基金资助项目
摘    要:氧化还原电位的调控对丁二酸发酵过程影响较大,而现有的丁二酸发酵过程动力学模型均未包含此重要参量。本研究首先进行五种氧化还原电位水平下的模型参数寻优,比较了Nelder-Mead算法与自适应遗传算法,采用后者进行参数优化。分析了氧化还原电位与动力学模型参数之间的函数关系,得到关联氧化还原电位的动力学模型。采用另外两种氧化还原电位水平下的实验数据进行模型验证,结果表明该模型具有较好的可靠性。

关 键 词:丁二酸发酵  氧化还原电位  动力学模型  自适应遗传算法  Nelder-Mead算法  参数优化

Kinetic Models of Succinic Acid Fermentation Process Relating to Redox Potential
QIAN Fei,ZHANG Shi,JIANG Min.Kinetic Models of Succinic Acid Fermentation Process Relating to Redox Potential[J].Control and Instruments In Chemical Industry,2010,37(10):10-13.
Authors:QIAN Fei  ZHANG Shi  JIANG Min
Affiliation:b(a.College of Automation and Electrical Engineering;b.College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing 210009,China)
Abstract:The effect of redox potential regulation on succinic acid fermentation process is great.Kinetic models of this process relating to redox potential(ORP) should be formed for optimum redox potential regulation.Adaptive genetic algorithm(AGA) was chosen to optimize the kinetic model parameters after the comparison of AGA and Nelder-Mead method.Parameters for the kinetic models of five ORP levels were determined.Then the relationship between ORP and those parameters was established.Furthermore,the verification of the kinetic models relating to ORP shows that the models can be well used between those ORP levels.
Keywords:succinic acid fermentation  redox potential  kinetic models  AGA  Nelder-Mead method  optimization of parameters
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