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| 气相色谱法测定脑通喷鼻微乳中麝香酮的含量 | |
| 引用本文： | 宋凤兰,陈颖,祝维峰,杨帆.气相色谱法测定脑通喷鼻微乳中麝香酮的含量[J].中南药学,2013,11(1):50-52. |
| 作者姓名： | 宋凤兰 陈颖 祝维峰 杨帆 |
| 作者单位： | 1. 广东药学院,广州,510006 2. 广东食品药品职业学院,广州,510520 3. 广东省广州市中医医院,广州,510130 |
| 摘 要： | 目的建立气相色谱法测定脑通喷鼻微乳中麝香酮的含量。方法采用Agilent DB-WAX毛细管色谱柱（30.0 m×0.449 mm×0.85μm）,FID检测器,程序升温：140℃维持8 min,再以30℃min-1升温至200℃维持10 min,进样口温度：250℃,检测器温度：280℃,外标法测定。结果麝香酮在浓度12～96μg·mL-1线性关系良好（r=0.999 8）,回收率为99.4%,RSD为1.8%（n=9）。结论该法简单、准确、重现性好,可用于脑通喷鼻微乳的质量控制。 |
| 关 键 词： | 微乳 气相色谱法 麝香酮 脑通喷鼻微乳 |
Determination of muscone in Naotong Penbi microemulsion by GC |
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| SONG Feng-lan , CHEN Ying , ZHU Wei-feng , YANG Fan.Determination of muscone in Naotong Penbi microemulsion by GC[J].Central South Pharmacy,2013,11(1):50-52. | |
| Authors: | SONG Feng-lan CHEN Ying ZHU Wei-feng YANG Fan |
| Affiliation: | 1*(1.Guangdong Pharmaceutical University,Guangzhou 510006;2.Guangdong Food and Drug Vocational College,Guangzhou 510520;3.Guangzhou Hospital of Traditional Chinese Medicine,Guangzhou 510130) |
| Abstract: | Objective To establish a GC method for the determination of muscone in Naotong Penbi microemulsion.Methods The chromatographic separation was carried out on the capillary column Agilent DB-WAX（30.0 m×0.449 mm×0.85 μm）,and FID was used as the detector.The column temperature was programmed at 140 ℃for 8 min and then rose to 200 ℃ at a rate of 30 ℃·min-1,maintaining for 10 min.The temperature of inlet and detector was 250 ℃ and 280 ℃.Results The good linear relationship was shown at 12-96 μg·mL-1（r=0.999 8）.The average recovery was 99.4%,RSD=1.8%.Conclusion This method is simple and reliable with a good reproduction and can be used for the control of Naotong Penbi microemulsion. |
| Keywords: | microemulsion GC muscone Naotong Penbi microemulsion |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
