蒙药河柏的化学成分研究

目的:研究河柏中的化学成分。方法:利用溶剂法进行提取和萃取分部,采用硅胶、Sephadex LH-20柱色谱法进行分离,利用理化鉴别及波谱分析技术鉴定化合物的结构。结果:从河柏中分离鉴定了11个化合物,分别为鞣酸-3,3′,4-三甲醚(1),鞣酸-3,3′-二甲醚(2),异鼠李素(3),山柰酚(4),3,5-二羟基-4-甲氧基苯甲酸(5),胡萝卜苷(6),6,7,10-三羟基-8-十八烯酸(7),槲皮素(8),没食子酸(9),棕榈酸(10),棕榈酸-α-单甘油酯(11)。结论:除化合物8,9,其他化合物均为首次从该种植物中得到,其中化合物1,2,5,7,10,11为首次从该属植物中得到。

Chemical constituents from Myricaria alopecuroides

Objective :To investigate the chemical constituents in the leaves and branches of Myricaria alopecuroides. Method : Solvent extraction method was employed to extract and partition. The chemical constituents were isolated by column chromatography on silica gel, Sephadex LH-20, highly porous resin HP-20. The structures of the compounds were elucidated on the basis of physiochemical properties and spectral analysis. Result : Eleven compounds were isolated from this plant and identified as ellagic acid 3,3',4-trimethylether ( 1 ), ellagic acid 3,3'-dimethylether ( 2 ), isorhamnetin ( 3 ), kaempferol ( 4 ), 3, 5-dihydroxy-4-methoxybenzoic acid ( 5 ), daucosterol ( 6 ), 6,7,10-trihydroxy-8-octadecenoic acid ( 7 ), quercetin ( 8 ), gallic acid ( 9 ), palmitic acid ( 10 ), hexadecanoic acid, 2,3-dihydroxypropyl ester ( 11 ). Conclusion : Except 8 and 9 , all compounds were isolated from M. alopecuroides for the first time. Compound 1, 2, 5, 7, 10, 11 were obtained from the genus Myricaria for the frist time.