| 肝癌肝移植术后复发转移的防治策略和靶向免疫治疗 |
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| 引用本文： | 秦小琰,刘彦尧,康权.肝癌肝移植术后复发转移的防治策略和靶向免疫治疗[J].器官移植,2022(2):271-276. |
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| 作者姓名： | 秦小琰 刘彦尧 康权 |
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| 作者单位： | 重庆医科大学附属儿童医院渝中院区普通创伤外科;重庆医科大学附属第一医院肝胆外科 |
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| 基金项目： | 重庆市卫生计生委医学科研计划项目(2017MSXM041)。 |
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| 摘 要： | 随着肝移植技术的发展和成熟,肝移植已成为治疗肝细胞癌(肝癌)的重要治疗手段之一,术后肿瘤复发转移是影响受者长期生存的重要原因之一,研究肝癌肝移植术后肿瘤复发转移的防治策略是提高肝癌肝移植受者临床疗效的关键.对肝癌肝移植受者肿瘤复发转移进行密切监测、积极预防、早期诊断,综合手术治疗、局部治疗特别是靶向免疫治疗等在内的多种...
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| 关 键 词： | 肝移植 肝细胞癌 复发 转移 免疫抑制剂 射频消融 经导管动脉化疗栓塞 靶向治疗 |
Prevention and therapeutic strategies and targeted immunotherapy for hepatocellular carcinoma recurrence and metastasis after liver transplantation |
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| Qin Xiaoyan,Liu Yanyao,Kang Quan.Prevention and therapeutic strategies and targeted immunotherapy for hepatocellular carcinoma recurrence and metastasis after liver transplantation[J].Ogran Transplantation,2022(2):271-276. |
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| Authors: | Qin Xiaoyan Liu Yanyao Kang Quan |
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| Affiliation: | (Department of General Surgery and Trauma Surgery of Yuzhong District,Children’s Hospital of Chongqing Medical University,Key Laboratory of Child Development and Disorders of Ministry of Education,National Clinical Research Center for Child Health and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China;不详) |
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| Abstract: | With the development and maturity of liver transplant techniques,liver transplantation has become one of the vital treatment options for hepatocellular carcinoma(HCC).Postoperative recurrence and metastasis of HCC after liver transplantation is one of critical factors that affect the long-term survival of recipients.Exploring the prevention and therapeutic strategies for HCC recurrence and metastasis after liver transplantation plays a pivotal role in improving the clinical efficacy of liver transplantation for HCC recipients.Intimate monitoring,active prevention,early diagnosis,comprehensive surgical treatment and local treatment,especially targeted immunotherapy,and individualized prevention and therapeutic strategies are of significance for the prevention and treatment of HCC recurrence and metastasis after liver transplantation.In this article,the monitoring,diagnosis,prevention and treatment of tumor recurrence and metastasis after liver transplantation for HCC were reviewed,aiming to provide reference for the prevention and treatment of tumor recurrence and metastasis after liver transplantation,enhancing clinical efficacy of liver transplantation and prolonging the survival of recipients. |
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| Keywords: | Liver transplantation Hepatocellular carcinoma Recurrence Metastasis Immunosuppressant Radiofrequency ablation Transcatheter arterial chemoembolization Targeted therapy |
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