| ~(89)Sr治疗前列腺癌骨转移临床观察 |
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| 引用本文： | 王庆祝,孟玉葆,韩星敏.~(89)Sr治疗前列腺癌骨转移临床观察[J].医药论坛杂志,2009(7). |
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| 作者姓名： | 王庆祝 孟玉葆 韩星敏 |
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| 作者单位： | 郑州大学第一附属医院核医学科; |
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| 摘 要： | 目的评价放射性核素89锶(89Sr)在前列腺癌骨转移中的治疗效果和不良反应。方法观察前列腺癌骨转移并伴有不同程度骨痛患者66例,使用89SrCl2静脉注射治疗,观察其镇痛效果、骨转移灶的变化、前列腺特异性抗原(PSA)及不良反应等。结果66例患者接受89Sr治疗后,止痛的总有效率达89.4%(59/66),无效10.6%(7/66),骨转移灶有明显减少。对PSA有不同程度的下降。所有治疗者均未发现严重的不良反应和毒副作用。结论89Sr治疗前列腺癌骨转移疼痛效果明显,对前列腺癌骨转移灶亦有治疗作用,是一种安全有效的方法。
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| 关 键 词： | 锶 放射性核素治疗 前列腺癌 骨转移癌 |
Strontium-89-chloride Therapy in Prostate Cancer with Bone Metastases |
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| WANG Qingzhu,Meng Yubao,Han XingminThe First Affiliated Hospital,Zhengzhou University,Zhengzhou ,China.Strontium-89-chloride Therapy in Prostate Cancer with Bone Metastases[J].Journal of Medical Forum,2009(7). |
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| Authors: | WANG Qingzhu Meng Yubao Han XingminThe First Affiliated Hospital Zhengzhou University Zhengzhou China |
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| Affiliation: | WANG Qingzhu,Meng Yubao,Han XingminThe First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052,China |
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| Abstract: | Objective To estimate curative efficacy and toxicity of 89Sr in treatment of bone metastases from prostate cancer.Methods 89Sr-chloride were administrated iv for palliative treatment of metastatic bone pain in 66 cases of bone metastases from prostate cancer.The curative effects in patients were investigated,including palliation of pain,change of metastatic focus,tumor sign of PSA,and adverse reaction.Results The total palliation rate was 89.4%(59/66),inefficiency rate was 10.6%(7/66),while metastatic focus... |
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| Keywords: | Strontium Radionuclide therapy Prostate cancer Bone metastases cancer |
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