| 克山病致病因素与心肌内甲状腺激素代谢改变及其机制和意义的探讨 |
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| 引用本文： | 刘晓亮,张颖.克山病致病因素与心肌内甲状腺激素代谢改变及其机制和意义的探讨[J].地方病通报,1995,10(1):53-56. |
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| 作者姓名： | 刘晓亮 张颖 |
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| 作者单位： | 白求恩医科大学地方病研究所，白求恩医科大学校直属医院 |
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| 摘 要： | 用克山病病区粮饲养动物，观察心肌内甲状腺激素代谢的改变并探讨其对克山病心肌病变的意义。结果病区粮组：１．心肌Ｔ４５＇－脱单碘酶活性降低；２．心肌组织内源Ｔ３含量减少；３．心肌线粒体α－磷酸甘油脱氢酶（α－ＧＰＤ）活性下降；４．心肌内心钠素含量增加；５．心肌组织内自由基代谢紊乱。上述改变当补充Ｓｅ和／或ＶＥ后均可恢复至正常。表明：克山病病区粮饲料中的致病因素能够导致心肌甲状腺激素的代谢紊乱，并使心肌
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| 关 键 词： | 克山病 甲状腺激素 心肌 动物实验 |
Studies on the Relationship between the Pathogenic Factors of Keshan Disease and Changes of Thyroid Hormone Metabolism in Myocardial Tissue and on the Mechanism and Meanings |
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| Liu Xiaoliang,Yue Lijie,Wang Fan,Liu Songyan.Studies on the Relationship between the Pathogenic Factors of Keshan Disease and Changes of Thyroid Hormone Metabolism in Myocardial Tissue and on the Mechanism and Meanings[J].Endemic Diseases Bulletin,1995,10(1):53-56. |
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| Authors: | Liu Xiaoliang Yue Lijie Wang Fan Liu Songyan |
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| Abstract: | |
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| Keywords: | Keshan Disease Thyroid hormone Myocardium Animal experiment |
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