儿童阻塞性睡眠呼吸暂停/低通气综合征与肥胖的相关性调查研究

目的研究儿童阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)与肥胖的关系及危险因素。方法选择200例单纯性肥胖儿和100例正常体重儿,分析OSAHS患病率及相关因素。结果肥胖组OSAHS患病率显著高于对照组(P<0.01),分别分为肥胖伴OSAHS组、肥胖非OSAHS组、正常体重伴OSAHS组和正常体重非OSAHS组,各组BMI标准值、OAI、AHI、LSaO2、CAI、睡眠效率差异均有统计学意义(P<0.01)。BMI标准值与OAI、AHI、CAI、睡眠效率呈正相关,与LSaO2呈负相关(P<0.05)。对比OSAHS患儿和非OSAHS患儿相关因素,肥胖、扁桃体肿大、腺样体肿大、颈围等差异均有统计学意义(P<0.05),肥胖、扁桃体肿大、腺样体肿大是儿童OSAHS患病危险因素(P<0.05)。结论肥胖显著增加儿童患OSAHS可能,与OSAHS严重程度密切相关。

Correlation of obstructive sleep apnea/hypopnea syndrome and obesity in children

Objective To study the relationship of obstructive sleep apnea/hypopnea syndrome （OSAHS） and obesity in children, and risk factors of OSAHS. Methods A total of 200 cases of simple obese children and 100 normal weight chil- dren were selected, and OSAHS prevalence and related factors were analyzed. Results The obese group OSAHS prevalence was significantly higher （P 〈 0.01）, and respectively divided into obese patients with OSAHS group and obese non-OSAHS group, and normal weight with OSAHS group and normal weight non-OSAHS group. The value of the differences of BMI standard values, OAI, AHI, LSaO2, CAI, sleep efficiency were statistically significant （P 〈 0.01）. BMI standard values and OAI, AHI, CAI, sleep efficiency were positively correlated, and LSaO2 was negatively correlated （P 〈 0.05）. Contrast to OSAHS children and children with non-OSAHS related factors, the differences of obesity, enlarged tonsils and adenoid enlarge- ment, neck circumference were statistically significant （P 〈 0.05）; obesity, enlarged tonsils, adenoids swollen large were risk factors of children OSAHS （P 〈 0.05）. Conclusion Obesity might increase suffering from OSAHS in children and is closely related to OSAHS severity.