| 箬叶多糖对小鼠实验性四氯化碳致肝损伤的作用 |
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| 引用本文： | 陈春英 丁玉强 Elhag A ELMAHADI周井炎 李 焰 徐辉碧.箬叶多糖对小鼠实验性四氯化碳致肝损伤的作用[J].中国药理学与毒理学杂志,1996,3(3):237-238. |
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| 作者姓名： | 陈春英 丁玉强 Elhag A ELMAHADI周井炎 李 焰 徐辉碧 |
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| 作者单位： | 华中理工大学化学系 |
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| 摘 要： | 箬叶多糖对小鼠实验性四氯化碳致肝损伤的作用陈春英丁玉强ＥｌｈａｇＡＥＬＭＡＨＡＤＩ１周井炎李焰徐辉碧（华中理工大学化学系，武汉４３００７４；１ＥｌｇａｚｉｒａＵｎｉｖｅｒｓｉｔｙ，ＷａｄｅｎｉＰＯＢｏｘ４２，Ｓｕｄａｎ）箬叶是禾本科植物箬竹（Ｉｎｄｏ...
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| 关 键 词： | 箬叶多糖 四氯化碳 自由基类 肝 |
| 收稿时间： | 1995-7-11 |
Effects of Indocalamus tessellatus polysaccharides on carbon tetrachloride-induced liver injury in mice |
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| CHEN Chun-Ying, DING Yu-Qiang, Elhag A ELMAHADI, ZHOU Jing-Yan, LI Yan, XU Hui-Bi.Effects of Indocalamus tessellatus polysaccharides on carbon tetrachloride-induced liver injury in mice[J].Chinese Journal of Pharmacology and Toxicology,1996,3(3):237-238. |
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| Authors: | CHEN Chun-Ying DING Yu-Qiang Elhag A ELMAHADI ZHOU Jing-Yan LI Yan XU Hui-Bi |
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| Affiliation: | (Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074; 1. Abu Haraz#CCollege, Elgazira University, Wadeni PO Box 42, Sudan) |
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| Abstract: | Indocalamus tessellatus polysac- charides (ITPS) were extracted from the dry bamboo leaves of Indocalamus tessellatus with 85% ethanol (FE), 95℃ water (FⅠ), 5% NaOH (FⅢ-1, FⅢ-2) and 20% NaOH (FⅣ). Effects of these ITPS on liver of 6% CCl4 oil solution 10 mL·kg-1-treated mice were studied. Various fractions of ITPS 80 mg·kg-1 ip respectively, once a day for 7 d significantly inhibited the MDA formation in hepatic mitochodrion and microsome, decreased the microviscosity of hepatic mitochodrial membrane and increased the SOD activity of liver. These results suggest that ITPS are protective against CCl4-induced liver damage. |
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| Keywords: | Indocalamus tessellatus polysaccharides carbon tetrachloride free radicals liver |
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