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| 脑心通治疗血管性认知障碍的临床研究 | |
| 引用本文： | 刘汉兴,章军建,王庆,郭宏伟.脑心通治疗血管性认知障碍的临床研究[J].卒中与神经疾病,2011,18(2):103-105. |
| 作者姓名： | 刘汉兴 章军建 王庆 郭宏伟 |
| 作者单位： | 1. 武汉大学中南医院神经内科,430071 2. 武汉市第九医院神经内科 3. 武汉市武昌铁路医院内科 |
| 摘 要： | 目的评价脑心通胶囊治疗血管性认知障碍的临床疗效和安全性。方法本研究从三个分中心招募血管性认知功能障碍(VCI)患者240例,并随机分为治疗组121例,其中无痴呆血管认知功能障碍(VCIND)患者45例,血管性痴呆(VaD)患者76例;对照组120例,其中VCIND患者44例,VaD患者76例。治疗组给予脑心通胶囊每日口服3次,每次4粒;对照组给予复方丹参片每日口服3次,每次4粒,连续服用3月。比较不同阶段的VCI患者治疗前后简易智能精神状态量表(MMSE)、日常生活能力量表(ADL)的变化。结果治疗组VCIND患者治疗后MMSE和ADL评分均有明显改善,差异有统计学意义(P<0.01)。治疗组VaD患者治疗后MMSE略有改善,差异无统计学意义(P>0.05),而ADL评分有改善,差异有统计学意义(P<0.01)。结论脑心通胶囊能够改善无痴呆血管性认知障碍(VCIND)患者的认知功能。 |
| 关 键 词： | 脑心通 血管性认知障碍 临床研究 |
A clinical observation of the treatment with Naoxintong capsule in the vascular cognitive impairment |
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| Liu Hanxing,Zhang Junjian,Wang Qing,et al..A clinical observation of the treatment with Naoxintong capsule in the vascular cognitive impairment[J].Stroke and Nervous Diseases,2011,18(2):103-105. | |
| Authors: | Liu Hanxing Zhang Junjian Wang Qing |
| Affiliation: | Liu Hanxing*,Zhang Junjian*,Wang Qing,et al.*Department of Neurology,Zhongnan Hospital,Wuhan University,Wuhan 430071 |
| Abstract: | Objective To assess the efficacy and safety of Naoxintong capsule in vascular cognitive impairment(VCI).Methods 241 patients with VCI were randomly divided into the treatment group n=121,VCI without dementia(VCIND):45,vascular dementia(VaD):76] and the control group(n=120,VCIND:44,VaD:76).The cases of treatment group were treated with Naoxintong capsule(4 tables Tid) and the control group were treated with Dan-shen(4 tables Tid).The duration of therapy was three months.MMSE and ADL were used to evaluate ou... |
| Keywords: | Naoxintong Vascular cognitive impairment Clinical study |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
