Processing methods for making porous bioactive glass-based scaffolds—A state-of-the-art review |
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| Authors: | Francesco Baino Elisa Fiume Jacopo Barberi Saeid Kargozar Juliana Marchi Jonathan Massera Enrica Verné |
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| Affiliation: | 1. Department of Applied Science and Technology, Institute of Materials Physics and Engineering, Politecnico di Torino, Torino, Italy;2. Department of Anatomy and Cell Biology, Tissue Engineering Research Group (TERG), School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;3. Center for Natural Sciences and Humanities, Federal University do ABC, Santo André, Brazil;4. Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland |
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| Abstract: | Bioactive glasses exhibit the unique ability of bone bonding, thus creating a stable interface by stimulating bone cells toward mechanisms of regeneration and self-repair activated by ionic dissolution products. Therefore, 3D glass-derived scaffolds can be considered ideal porous templates to be used in bone tissue engineering strategies and regenerative medicine. This review provides a comprehensive overview of all technological aspects relevant to the fabrication of bioactive glass scaffolds, including the fundamentals of materials processing, a summary of the conventional porogen, and template-based methods and of recent additive manufacturing technologies, which are promising for large-scale production of highly reproducible and reliable implants suitable for a wide range of clinical applications. |
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| Keywords: | additive manufacturing bioactive glasses bioceramics scaffolds |
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