间日疟原虫红细胞内期电镜观察

间日疟原虫裂殖子钻入红细胞后,早期环状体呈哑铃形,其纳虫空泡内膜状物质通过红细胞中狭窄通道排出。滋养体形状不规则,或呈卵圆形,由单层表膜包绕,细胞质内具有无嵴线粒体,纳虫空泡中有电子致密颗粒。配子体形状规则,几乎充满被寄生的红细胞,由两层表膜包绕,细胞质内具有有嵴线粒体。雌配子体细胞质内核糖体、嗜锇小体和线粒体都比雄配子体丰富。被寄生的红细胞的3个主要变化为出现小泡、细胞质裂隙和凹窝小泡复合物。后者沿红细胞表膜分布,可能是薛氏小点。

ULTRASTRUCTURE OF ERYTHROCYTIC STAGE OF PLASMODIUM VIVAX IN HUMANS

After the merozoite entered the erythrocyte,the membrane debris in the parasitophorous vacuoles of early ring form was passed out through a narrow external aperture in erythro-cyte to the exterior.The trophozoite was oval or irregular in shape.Ingestion of host cell cytoplasm occurred cystostomally.The asexual parasite possessed acristate mitochondria and was surrounded by a single-membraned pellicle.The gametocyte possessed cristate mitochondria and was surrounded by two unit membranes.The cytoplasm of mature macrogametocytes contained many ribosomes,mitochondria and osmiophilic bodies and a small nucleus while microgametocytes contained fewer ribosomes,osmiophilic bodies and mitochondria and a large nucleus.Three characteristic morphological alterations were observed within the host cells,that is,small vesicles,cytoplasmic cleft and caveola-vesicle complex.The clefts within the cytoplasm of the host erythrocytes were present in all human malarial parasites.The small vesicles distributed all over the cytoplasm were surrounded by a unit membrane.The caveola-vesicle complex consisted of caveolae was surrounded by small vesicles and probably corresponds to a Schuffner's dot.(Figs.1-13)