| 空间流行病学与分子流行病学结合分析在结核病研究中的应用进展 |
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| 引用本文： | 陈文明,周庆荣,王晓萌,毛辉曙,王萍,周琳,王伟炳.空间流行病学与分子流行病学结合分析在结核病研究中的应用进展[J].中华流行病学杂志,2016,37(12):1683-1686. |
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| 作者姓名： | 陈文明 周庆荣 王晓萌 毛辉曙 王萍 周琳 王伟炳 |
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| 作者单位： | 200032 上海, 复旦大学公共卫生学院流行病学教研室, 教育部公共卫生安全重点实验室, 健康风险预警治理协同创新中心;324100 江山市疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心结防所;324100 江山市疾病预防控制中心;324100 江山市疾病预防控制中心;310051 杭州, 浙江省疾病预防控制中心结防所;200032 上海, 复旦大学公共卫生学院流行病学教研室, 教育部公共卫生安全重点实验室, 健康风险预警治理协同创新中心 |
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| 基金项目： | 英国国际发展部资助的中英全球卫生支持项目（GHSP-CS-OP302）；国家自然科学基金（81673233）；浙江省科技厅重大专项计划项目（2014C03034） |
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| 摘 要： | 空间流行病学和分子流行病学方法在结核病研究中已广泛使用，但二者均具有各自的局限性，而二者的结合则为结核病研究提供了新的思路和方法。文中所有引用文章均来自中国知网、万方数据知识服务平台、PubMed和Web of Science四个数据库。空间流行病学和分子流行病结合的方法在国外的结核病研究中已广泛使用，在确定区域地方性的流行菌株基因型、结核病传播方式及危险因素分析、耐药结核病、结核病防控措施等方面均具有重要意义，值得国内该领域的研究学者和疾病防控工作者进行借鉴和学习。
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| 关 键 词： | 结核病 空间流行病学 分子流行病学 |
| 收稿时间： | 2016/7/14 0:00:00 |
Integration of spatial epidemiology and molecular epidemiology used for study on tuberculosis |
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| Chen Wenming,Zhou Qingrong,Wang Xiaomeng,Mao Huishu,Wang Ping,Zhou Lin and Wang Weibing.Integration of spatial epidemiology and molecular epidemiology used for study on tuberculosis[J].Chinese Journal of Epidemiology,2016,37(12):1683-1686. |
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| Authors: | Chen Wenming Zhou Qingrong Wang Xiaomeng Mao Huishu Wang Ping Zhou Lin and Wang Weibing |
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| Affiliation: | Department of Epidemiology, School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Shanghai 200032, China;Center for Disease Control and Prevention of Jiangshan, Jiangshan 324100, China;Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Center for Disease Control and Prevention of Jiangshan, Jiangshan 324100, China;Center for Disease Control and Prevention of Jiangshan, Jiangshan 324100, China;Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China;Department of Epidemiology, School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Shanghai 200032, China |
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| Abstract: | Spatial epidemiology and molecular epidemiology have been widely used in the studies of tuberculosis (TB), but each with limitations. Integration of the two methods provides new ideas and methods in TB research. All referenced articles are from CNKI, Wan Fang database, PubMed database and Web of Science database. Method of combining spatial epidemiology and molecular epidemiology has been widely used in determining the local epidemic strains of TB genotype, the transmission mechanism, risk factors of TB, drug-resistant TB, as well as evaluating the effectiveness of TB prevention and control measures. Application of the combined methods is of important significance in the studies of TB, thus worthy to be further introduced to researchers and disease prevention and control workers in this country. |
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| Keywords: | Tuberculosis Spatial epidemiology Molecular epidemiology |
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