翻白叶树根的化学成分研究

目的 研究翻白叶树Pterospermum heterophyllum根的化学成分.方法 应用多种色谱技术进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构.结果 从翻白叶树根95％乙醇提取物中分离得到12个化合物,分别鉴定为莨菪苷(1)、2,6-二甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷(2)、3-甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷(3)、4-羟基-2-甲氧基-苯酚-1-O-β-D-吡喃葡萄糖苷(4)、甲基熊果苷(5)、(+)-南烛木树脂酚-3 α-O-β-D-吡喃葡萄糖苷(6)、(-)-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷(7)、(-)-南烛木树脂酚-2 α-O-β-D-吡喃葡萄糖苷(8)、(-)-异落叶松树脂酚-6-O-β-D-吡喃葡萄糖苷(9)、(-)-8,8’-二甲氧基-开环异落叶松树脂酚-1-O-β-D-吡喃葡萄糖苷(10)、(+)-3-oxo-α-ionyl-O-β-D-glucopyranoside( 11)、roseoside( 12).结论 化合物1～11为首次从该属植物中分离得到.

Studies on chemical constituents from roots of Pterospermum heterophyllum

Objective To study the chemical constituents from the roots of Pterospermum heterophyllum.Methods The chemical constituents were isolated and purified by chromatographic techniques,and their structures were identified by physicochemical characteristics and spectroscopic analyses.Results Twelve compounds were isolated from the 95% EtOH extract in the roots of P.heterophyllum and were identified as scopolin(1),2,6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside(2),3-methoxy-4hydroxyphenol-1-O-β-D-glucopyranoside(3),4-hydroxy-2-methoxyphenol-1-O-β-D-glucopyranoside(4),methylarbutin(5),(+)lyoniresinol-3α-O-β-D-glucopyranoside(6),()-lyoniresinol-3α-O-β-D-glucopyranoside(7),()-lyoniresinol-2α-O-β-D-glucopyranoside(8),()-isolariciresinol-6-O-β-D-glucopyranoside(9),()-8,8′-dimethoxy-l-O-(β-D-glucopyranosyl)secoisolariciresinol(10),(+)-3oxo-α-ionyl-O-β-D-glucopyranoside(11),and roseoside(12).Conclusion Compounds 1—11 are isolated from the plants in Pterospermum Schreber for the first time.