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IL-6在心衰大鼠心肌组织中表达及GHRP的干预作用
引用本文:赵勇,田国忠,李梅秀,欧叶涛,孙权,尹兴忠. IL-6在心衰大鼠心肌组织中表达及GHRP的干预作用[J]. 黑龙江医药科学, 2011, 34(4): 31-32
作者姓名:赵勇  田国忠  李梅秀  欧叶涛  孙权  尹兴忠
作者单位:佳木斯大学基础医学院解剖学教研室,黑龙江佳木斯,154007
基金项目:黑龙江省教育厅科研项目,编号:11531386
摘    要:目的:研究心衰大鼠心肌组织中白细胞介素-6 (Interleukin-6,IL-6)的表达以及生长素释放肤(Growth hormonereleasing peptide,GHRP)对其产生的干预作用.方法:以阿霉素制备大鼠心衰模型,采用免疫组织化学染色法检测各组大鼠心肌组织中IL-6的表达变化.结果:模型组与正常组相...

关 键 词:生长素释放肽  慢性心力衰竭  白细胞介素-6

The effect of GHRP on the expression of IL-6 in myocardium of rats with heart failure
ZHAO Yong,TIAN Guo-zhong,LI Mei-xiu,OU Ye-tao,SUN Quan,YIN Xing-zhong. The effect of GHRP on the expression of IL-6 in myocardium of rats with heart failure[J]. Heilongjiang Medicine and Pharmacy, 2011, 34(4): 31-32
Authors:ZHAO Yong  TIAN Guo-zhong  LI Mei-xiu  OU Ye-tao  SUN Quan  YIN Xing-zhong
Affiliation:ZHAO Yong,TIAN Guo-zhong,LI Mei-xiu,OU Ye-tao,SUN Quan,YIN Xing-zhong(Department of Anatomy,Basic Medical College,Jiamusi University,Jiamusi 154007,China)
Abstract:Objective:To study the change of the expression of IL-6 in myocardium of rats with heart failure and the effect of GHRP on which.Methods:Rat model of heart failure was prepared by injecting Adriamycin,and use immunohistochemical method to examine the change of the density of immunological positive cell of IL-6.Results: Compared with normal group,the expression of IL-6 of model group in myocardium increased.The differences were statistically significant.Compared with model group,the expression of IL-6 of tre...
Keywords:Growth hormone releasing peptide  Chronic heart failure  Interleukin-6  
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