地方性甲状腺肿、地方性克汀病流行区人群血清、水、土微量元素调查报告

本文就我省大别山区霍山县地方性甲状腺肿和地方性克汀病流行区——太平乡185例成人血清铜、锌、锰、镁测定结果与非病区正常成人495例均值相比较,发现锰、铜、铜/锌比值高:锌、镁低,均具有统计学意义。对当地水、土壤检测这些元素也有相应发现。推测在当地地甲病和地克病的病因和发病原理上,除缺碘为基础外,这些元素含量的异常也可能起着重要影响。在今后的防治中,除补碘外,对这些有关元素也应考虑作相应补充或驱除。

Investigation of Trace Elements in the Epidemic Area of Endemic Goiter and Cretinism

This report presents the findings of serum copper, zinc, manganese and magnesium in 185 adults in Taiping Village, the epidemic area of endemicgoiter and cretinism, in Dabie Mountain District of Huoshan County of Anhui province. In comparison with the mean values of 495 normal adults in the nonepidemic area, manganese, copper, and copper/zinc rate are increased while zinc and magnesium are decreased, all statistically significant. Corresponding changes of these elements in water and soil are found by analyses. It is postulated that besides the base of iodine deficiency, the etiology and pathogenesis may involve the abnormalities of these elements.The ways of prevention and therapy should be considered to supplement or eliminate these elements correspondingly in addition to iodine supply.