The concept of the integrative activities of neurons and mechanisms of neuroplasticity

The current state of the problem of the integrative activities of neurons is considered on the basis of literature data and system analysis of results obtained in the studies of mechanisms of a simple form of learning in the edible snail. We describe postsynaptic mechanisms of mediation, excitatory inputs that converge to a neuron, and their specific molecular transformations and integration inside the cytoplasm and nucleus. We propose a hypothetical scheme of intracellular integration of excitatory inputs in a neuron during learning as a basis for long-term postsynaptic plastic changes.