昆布提取物对小鼠免疫功能及抗疲劳能力的影响

目的] 观察昆布提取物（AEK）对小鼠免疫功能及抗疲劳能力的影响。方法] 昆明种小鼠，体质量18~22 g，40只，分为4组，分别为AEK小剂量组（21.2 g/kg）、AEK大剂量组（106 g/kg）、生理盐水空白对照组和阳性对照甲状腺素组（20 mg/kg）.灌胃给药10 d后，分别测定AEK对小鼠腹腔巨噬细胞吞噬功能和淋巴细胞转化功能的影响，以及对二硝基氯苯（DNCB）致耳肿胀和抗疲劳能力的影响。结果] AEK可提高小鼠腹腔吞噬细胞的吞噬百分率及吞噬指数；促进植物凝血素（PHA）诱导的淋巴细胞转化；促进DNCB引起的皮肤迟发超敏反应及溶血素抗体的生成；延长小鼠在水中游泳时间。结论] AEK对小鼠非特异性免疫、细胞免疫及体液免疫均有增强作用，并能提高小白鼠的抗疲劳能力。

Influences of aqueous extract of kelp on immune function and anti-fatigue in mice

By comparing and analyzing the records of slow pluse in various editions of Diagnostics of Traditional Chinese Medicine, it is indicated that slow pluse pertains to abnormal pluse, and there is no physiological or pathological divide in slow pluse. The so-called normal slow pluse and morbid one belong to a conceptual confusion. The slow pluse is characterized by two factors, including four pulsations in a breath, flaccidity and lassitude, and it suggests dampness and deficiency of spleen and stomach.