| 蛋白标志物在辐射损伤中的应用 |
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| 引用本文： | 马铁军,王毅,杨莹,冯伟,李冕.蛋白标志物在辐射损伤中的应用[J].国际放射医学核医学杂志,2010,34(3). |
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| 作者姓名： | 马铁军 王毅 杨莹 冯伟 李冕 |
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| 作者单位： | 解放军第537医院防护科,陕西宝鸡,721006 |
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| 摘 要： | 机体暴露于电离辐射下,一系列分子表达活性将发生变化,特异性改变的蛋白质可作为标志物用于辐射损伤的鉴别分类、治疗防控以及动态观察.该文综述了目前已经确定的或具有潜在功能的数种辐射损伤蛋白标志物的应用价值,介绍了多种蛋白标志物综合分析用于辐射损伤的诊断和治疗的目前研究进展.
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| 关 键 词： | 蛋白质类 生物学标记 辐射损伤 |
The applications of protein biomarkers in radiation injury |
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| MA Tie-jun,WANG Yi,YANG Ying,FENG Wei,LI Mian.The applications of protein biomarkers in radiation injury[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(3). |
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| Authors: | MA Tie-jun WANG Yi YANG Ying FENG Wei LI Mian |
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| Abstract: | When people are exposed to ionising radiation, a series of molecules changing rapidly followed. Protein biomarkers of radiation injury are critical for triage, treatment, and follow-up of patients.This article reviews the application value of the definitive protein biomarkers with potential function, and introduces the progress in latest research of the multiparametric protein biomarkers analysis for diagnosis and therapy of radiation injury. |
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| Keywords: | Proteins Biological markers Radiation injury |
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