电离辐射诱发的非靶效应及其生物学意义

辐射诱发的非靶效应包括基因组不稳定性、旁效应、断裂因子以及亲代受照射后的遗传效应。非靶效应在辐射致癌、辐射防护、放射治疗、辐射危险评估以及细胞衰老等方面有重要的生物学意义。本文主要从辐射诱发的基因组不稳定性和旁效应两方面介绍辐射诱发的非靶效应及其生物学意义。

Potential Biological Implications of Ionizing Radiation Induced Non-targeted Effects

With the development of radiobiology,the studies on non-targeted effects induced by ionizing radiation have become a hotspot of biology.The discovery of non-targeted effects has challenged to traditional theories of radiobiology.Non-targeted effects induced by ionizing radiation include genomic instabilities and bystander effects.Although the mechanisms of non-targeted effects induced by ionizing radiation is not yet completely clear now,the importance of non-targeted effects can not be ignored.This paper i...