| 新型心肌灌注显像剂^99mTc—tetrofosmin诊断冠心病的价值 |
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| 引用本文： | 唐志宏,黄兰君,彭武和,王国英,曾建华,刘伊丽.新型心肌灌注显像剂^99mTc—tetrofosmin诊断冠心病的价值[J].中国临床医学影像杂志,2001,12(1):20-21. |
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| 作者姓名： | 唐志宏 黄兰君 彭武和 王国英 曾建华 刘伊丽 |
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| 作者单位： | 第一军医大学南方医院，广东 广州 510515 |
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| 基金项目： | 本论文为广东省医药卫生科研基金资助(A1998354) |
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| 摘 要： | 目的：探讨新型心肌灌注显像剂^99mTc-tetrofosmin诊断冠心病的临床价值。材料与方法：对59例确诊或疑诊并已行冠状动脉造影的患者进行运动。静息心肌灌注断层显像，分别在运动高峰及静息状态静脉注射^99mTc-tetrofosmin740MBq后30－60min按常规方法做SPECT断层采集。结果：在注射^99mTc-tetrofosmin的后无任何不适反应，并获得良好心肌断层图像，以冠状动脉造影结果为金标准，^99mTc-tetrofosmin诊断冠心病的灵敏度、特异性及准确度分别为89．1％，84．6％及88．1％。结论：^99mTc-tetrofosmin具有标记简便，给药后无需脂餐促排、显像时间短、图像质量清晰及诊断准确度较高等特点，有着良好的临床应用前景。
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| 关 键 词： | 放射性核素显像 冠状动脉疾病 诊断 |
| 文章编号： | 1008-1062(2001)01-0020-02 |
| 修稿时间： | 2000年5月9日 |
The preliminary clinical
study of 99mTc-tetrofosmin for detecting CAD |
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| TANG Zhi-hong.The preliminary clinical
study of 99mTc-tetrofosmin for detecting CAD[J].Journal of China Clinic Medical Imaging,2001,12(1):20-21. |
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| Authors: | TANG Zhi-hong |
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| Abstract: | Objective: To assess the clinical value of 99mTc -tetrofosmin inthe diagnosis of coronary artery disease(CAD). Materials and Methods: Fifty-nine patients who had coronary angiography had myocardial perfusion imaging at 30～60 minutes after intravenous injection of 99mTc-tetrofosmin. The findings of stress and rest myocardial tomography were compared with coronary angiography. Results:No side effects had been discovered. Excellent myocardial images with high contrast were obtained.The sensitivity,specificity and accuracy of 99mTc-tetrofosmin in detecting CAD were 89.1%, 84.6% and 88.1%, respectively. Conclusions:99mTc-tetrofosmin perfusion tomography is a feasible and valuable means for identification of patient with CAD. |
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| Keywords: | radionuclide imaging coronary disease |
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