| 295例葛根素注射液不良反应分析 |
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| 引用本文： | 柳琳,饶跃峰,马葵芬,赵青威,张幸国.295例葛根素注射液不良反应分析[J].药品评价,2010,7(24):56-58. |
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| 作者姓名： | 柳琳 饶跃峰 马葵芬 赵青威 张幸国 |
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| 作者单位： | 浙江大学医学院附属第一医院,浙江杭州310003 |
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| 基金项目： | 浙江浦科技计划项目，浙江省中医药管理局资助项目 |
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| 摘 要： | 目的：总结葛根素注射液不良反应发生的类型及特点.方法：对2005～2009年浙江省药品不良反应监测中心接收到的295例葛根素注射液不良反应报告进行分析和总结.结果：葛根素注射液的不良反应临床表现主要为药物热、药疹、溶血及休克等症状,在高剂最（≥400mg/d）及连续用药时更易发生.结论：葛根素注射液不良反应的发生与多种因素有关,应用时应高警惕.
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| 关 键 词： | 葛根素注射液 药物不良反应 |
Analysis on 295 Cases of Adverse Drug Reactions Associated with Puerarin Injections |
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| LIU Lin,RAO Yue-feng,MA Kui-feng,ZHAO Qing-wei,ZHANG Xing-guo.Analysis on 295 Cases of Adverse Drug Reactions Associated with Puerarin Injections[J].Drug Evaluation,2010,7(24):56-58. |
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| Authors: | LIU Lin RAO Yue-feng MA Kui-feng ZHAO Qing-wei ZHANG Xing-guo |
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| Affiliation: | The First Affiliated Hospital, College of Medicine, Zhejiang University School of Medicine, Hangzhou 310003 |
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| Abstract: | Objective： To summarize the types and characteristics of adverse drug reactions（ADR）associated with Puerarin injections. Methods： 295 cases of ADRs associated with puerarin injection during 2005~2009 from Zhejiang drug adverse reaction monitoring center were analyzed and summarized. Results＂ Primary symptoms of ADR associated with puerarin injection were fever, anthesma, hemolysis and shock. It seemed that ADRs happened more often when high dosage （≥400mg/d）, or continuous administration were applied. Conclusion： ADRs associated with puerarin are correlative with multiple factors. |
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| Keywords: | Puerarin injection Adverse drug reactions |
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