蓝莓花青素在眼科疾病的研究进展

蓝莓又名越橘，它还有很多别名，如笃斯，都柿等，是营养价值极高的浆果，在我国主要种植于山东半岛和大小兴安岭等地区。它具有超强的抗氧化活性和清除自由基能力，归根结底是因为蓝莓中富含丰富的花青素。它还有许多优点，例如高效率、低毒和对人体的生物利用率为100%。蓝莓花青素可以降血压、降血脂，对由于糖尿病引起的毛细血管病有治疗作用，抗炎症、抗癌、预防老年痴呆、增强视力，消除眼睛疲劳、促进眼周微血管循环、延缓脑神经衰老，增强心肺功能等功效。本文主要以蓝莓的提取物花青素为代表来综述花青素的性质、药理作用以及在主要眼病如缓解视疲劳、屈光不正、眼表疾病、白内障、青光眼、视网膜病变等方面应用的最新研究进展。在未来发展进程中，如果能更加深入地研究出其药物作用机制，将会为眼科临床应用提供更多既有效又经济的药物，为广大患者带来福音。

Research progress in blueberry anthocyanin in eye disease

Blueberries, which can also be called cranberries, has many nicknames such as Benedict, persimmon and so on. It is a kind of berries which has high nutritional value and mainly cultivated in Shandong peninsula and large areas of Xiao Hinggan Mountains. It has strong antioxidant activity and radical scavenging ability because of the rich anthocyanins. It also has many advantages, such as the advantages of high efficiency, low toxicity and high bioavailability. Also, it can reduce blood pressure, hematic fat, to have remedial effect caused by diabetes capillaries disease anti-inflammatory, anti-tumor, preventing Alzheimer''s, helping support vision, decreasing the symptom of eye fatigue, promoting vascular circulation around our eyes, slowing down the aging of the retinal cell and prevent cardiovascular and cerebrovascular disease. This article mainly takes anthocyanin, which is extracted from blueberry for example to research its property, pharmacological effects and eye disease, such as slowing down the symptom of eye fatigue ametropia, ocular surface disease, cataract, glaucoma, retinopathy and so on. We believe that in the coming future, the pharmacological mechanism of procyanidins could be clarified much more clearly and exert its greater medical value. It will become effective drugs that provide more economic in ophthalmic clinical application and provides much more benefit to the patients.