| 头孢噻肟在输液中与6种注射剂配伍的稳定性研究 |
| |
| 引用本文： | 张渊,赵志英,钱漪.头孢噻肟在输液中与6种注射剂配伍的稳定性研究[J].中国药学杂志,1997,32(1):23-25. |
| |
| 作者姓名： | 张渊 赵志英 钱漪 |
| |
| 作者单位： | 上海市第一人民医院 |
| |
| 摘 要： | 目的:研究头抱噻肟( cefotaxime, CTX)在50g·L-1蔺萄糖输液中与维生素B6<\sub>等6种注射剂配伍的稳定性，为临床合理用药提供科学依据。方法:选择25.37℃在5h内观察配伍液的外观、pH及CTX紫外光谱的变化，用紫外分光光度法测定CTX的含量。结果:其稳定性与温度和pH有关。结论:在25℃，与6种注射剂配伍5h内都稳定可用;在37℃，与维生素C、氛茶碱注射剂配伍，则最好在3h内用完。
|
| 关 键 词： | 头饱噻肟 维生素B6 地塞米松磷酸钠 酚磺乙胺 维生素C 氨茶碱 法莫替丁 |
| 收稿时间： | 1996-04-12; |
Stability of cefotaxime compatibility with six kinds of injection in transfusion |
| |
| Zhang Yuan.Stability of cefotaxime compatibility with six kinds of injection in transfusion[J].Chinese Pharmaceutical Journal,1997,32(1):23-25. |
| |
| Authors: | Zhang Yuan |
| |
| Affiliation: | ( Zhang Y )，Zhao Zhiying(Zhao ZY )，Qian Yi(Qian Y |
| |
| Abstract: | OBJECTIVE:To study the sability of cefotaxime(CTX) mixed with vitamin B6etc. in 50g·L-1glucose injection solution, and provide a scientific basis for rationalized use of CTX. METHOD: The mixed solution caused the changes in the appearance and pH and CTX UV spectrum at 25, 37℃in 5 hours. The content of CTX was determined by UV spectrophotometer. RESULTS: The stability was related to the changes in temperature and pH. CONCLUSION: The solutions were all stable at 25℃ for 5 hours, and ideally used in 3 hours when compatibility with vitamin C, aminophylline
at 37℃. |
| |
| Keywords: | cefotaxime vitamin B 6 dexamethasone sodium phosphate etamsylate vitamin C aminophylline famotidine |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国药学杂志》浏览原始摘要信息 |
|
点击此处可从《中国药学杂志》下载全文 |
