| 芥子气的生殖毒性 |
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| 引用本文： | 贺茜,尚丽新,赵杰,肖良,王倩倩,聂菲,朱明学,张黎明.芥子气的生殖毒性[J].国外医学(药学分册),2011(6):442-444. |
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| 作者姓名： | 贺茜 尚丽新 赵杰 肖良 王倩倩 聂菲 朱明学 张黎明 |
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| 作者单位： | [1]第二军医大学长海医院妇产科,上海200433 [2]北京军区总医院妇产科,北京100700 [3]第二军医大学海医系防化医学教研室,上海200433 |
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| 基金项目： | 特需药品替代临床综合评价平台（2010ZXG0900X-005） |
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| 摘 要： | 芥子气是在多次战争中使用的最有效的化学毒剂之一。作为典型的双功能烃化剂，芥子气的急性毒性和中毒人员的临床救治已成为人们关注的重点，而对芥子气给环境造成的长期影响和中毒人员的远后效应关注不足。作为已知的致突变和致癌剂，芥子气的生殖毒性尚不明确。本文简要介绍国内外关于芥子气生殖毒性研究现状。
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| 关 键 词： | 芥子气 生殖毒性 化学毒剂 |
Reproductive toxicity of mustard gas |
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| HE Qian,SHANG Li-xin,ZHAO Jie,XIAO Liang,WANG Qian-qian,NIE Fei,ZHU Ming-xue,ZHANG Li-ming.Reproductive toxicity of mustard gas[J].Foreign Medical Sciences(Section of Pharmarcy),2011(6):442-444. |
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| Authors: | HE Qian SHANG Li-xin ZHAO Jie XIAO Liang WANG Qian-qian NIE Fei ZHU Ming-xue ZHANG Li-ming |
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| Affiliation: | 1. Department of Gynecology and Obstetrics, Changhai Hospital, the Second Military Medical University,Shanghai 200433, China;2. Department of Obstetrics and Gynecology, General Hospital of Beifing Military Region ,Beifing 100700, China; 3. Department of Chemical Defence Medicine ,Faculty of Naval Medicine, the Second Military Medical University, Shanghai 200433, China) |
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| Abstract: | Mustard gas, as one of the most effective chemical agents, has been used for many times in the past wars. As a typical bifunctional alkylating agent,the acute toxicity of mustard gas poisoning and the clinical treatment of poisoned victim have become a hot research topic in recent years,while the long-term environmental impact and the after-effects were far less con- cerned,and the reproductive toxicity of mustard gas was not clear. In this article,the research advances in reproductive toxicity of mustard gas are briefly reviewed. |
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| Keywords: | mustard gas reproductive toxicity chemical agents |
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