超声弹性应变比值对甲状腺结节良恶性的鉴别诊断价值

目的探讨超声弹性应变比值(SR)对甲状腺结节良恶性的鉴别诊断价值。方法 97例甲状腺结节患者,其中良性65例,恶性32例,采用超声弹性成像技术测量周围组织与结节的SR,比较良性与恶性结节间SR的差异,通过建立受试者工作特性曲线(ROC)来评价SR诊断甲状腺良恶性结节的价值。结果 65例良性及32例恶性甲状腺结节的SR值分别为1.41±0.73及6.57±4.34,差异有统计学意义。应用ROC曲线评价SR诊断甲状腺恶性结节的曲线下面积为0.982,取SR阈值为2.73时,敏感度、特异度、准确性、阳性预测值及阴性预测值分别为96.88%、96.92%、96.91%、93.94%和98.44%。结论超声弹性参数SR对甲状腺结节的良恶性鉴别有较好的应用价值。

The value of ultrasonic elastography strain ratio in differentiating benign from malignant thyroid nodules

Objective To explore the value of strain ratio （SR） in differentiating benign from malignant thyroid nodules. Methods Ninety - seven patients with benign （n = 65 ） or malignant （n = 32） thyroid nodules were enrolled in the study. The SR of normal surrounding tis- sues to thyroid nodules was calculated by ultrasonic elastography, and SRs of benign and malignant thyroid nodules were compared with independ- ent - samples T test, the diagnostic value of SR was evaluated by receiver operating characteristic curve. Results SRs of benign and malignant thyroid nodules were respectively 1.41 -sO. 73 and 6. 57 ＋4. 34, which had significant difference between them. The area under the curve was 0. 982 for SR with elnsography , took SR threshold of 2.73, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 96. 88%, 96. 92%, 96.91%, 93.94% and 98.44% respectively. Conclusion SR is an effective elasticity parameter and has good application value in differentiating benign from malignant thyroid nodules.