One‐Pot Double Benzylation of 2‐Substituted Pyridines using Palladium‐Catalyzed Decarboxylative Coupling of sp2 and sp3 Carbons期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

One‐Pot Double Benzylation of 2‐Substituted Pyridines using Palladium‐Catalyzed Decarboxylative Coupling of sp2 and sp3 Carbons

Authors:	Yaping Wang Xinjian Li Faqiang Leng Helong Zhu Jingya Li Dapeng Zou Yangjie Wu Yusheng Wu

Abstract:	An efficient and practical decarboxylative double benzylation method for various 2‐picolinic acids has been established by using a bimetallic catalytic system of palladium(II) chloride (PdCl₂) and silver(I) oxide (Ag₂O), which offered a variety of diarylmethane derivatives with moderate to good yields.

Keywords:	benzyl bromide sp2– sp3 cross‐coupling decarboxylation double benzylation 2‐picolinic acids